Vickery CD, Sherer M, Nick TG, Nakase-Richardson R, Corrigan JD, Hammond F, Macciocchi S, Ripley DL, Sander A. Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury. Objective: To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). Design: Prospective cohort study. Setting: Acute inpatient TBI rehabilitation. Participants: Participants were 1748 persons with TBI. Interventions: Not applicable. Main Outcome Measures: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. Results: Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. Conclusions: The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.
- Alcoholic intoxication
- Brain injuries
- Treatment outcome
ASJC Scopus subject areas
- Physical Therapy, Sports Therapy and Rehabilitation
Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury. / Vickery, Chad D.; Sherer, Mark; Nick, Todd G.; Nakase-Richardson, Risa; Corrigan, John D.; Hammond, Flora; Macciocchi, Stephen; Ripley, David L.; Sander, Angelle.In: Archives of physical medicine and rehabilitation, Vol. 89, No. 1, 01.01.2008, p. 48-55.
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