Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury

Chad D. Vickery, Mark Sherer, Todd G. Nick, Risa Nakase-Richardson, John D. Corrigan, Flora Hammond, Stephen Macciocchi, David L. Ripley, Angelle Sander

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Vickery CD, Sherer M, Nick TG, Nakase-Richardson R, Corrigan JD, Hammond F, Macciocchi S, Ripley DL, Sander A. Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury. Objective: To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). Design: Prospective cohort study. Setting: Acute inpatient TBI rehabilitation. Participants: Participants were 1748 persons with TBI. Interventions: Not applicable. Main Outcome Measures: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. Results: Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. Conclusions: The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.

Original languageEnglish (US)
Pages (from-to)48-55
Number of pages8
JournalArchives of Physical Medicine and Rehabilitation
Volume89
Issue number1
DOIs
StatePublished - Jan 2008
Externally publishedYes

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Alcohols
Drinking
Binge Drinking
Inpatients
Wounds and Injuries
Rehabilitation
Outcome Assessment (Health Care)
Traumatic Brain Injury
Hospital Emergency Service
Cohort Studies
Multivariate Analysis
Regression Analysis
Prospective Studies
Interviews
Blood Alcohol Content

Keywords

  • Alcoholic intoxication
  • Brain injuries
  • Rehabilitation
  • Treatment outcome

ASJC Scopus subject areas

  • Rehabilitation

Cite this

Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury. / Vickery, Chad D.; Sherer, Mark; Nick, Todd G.; Nakase-Richardson, Risa; Corrigan, John D.; Hammond, Flora; Macciocchi, Stephen; Ripley, David L.; Sander, Angelle.

In: Archives of Physical Medicine and Rehabilitation, Vol. 89, No. 1, 01.2008, p. 48-55.

Research output: Contribution to journalArticle

Vickery, Chad D. ; Sherer, Mark ; Nick, Todd G. ; Nakase-Richardson, Risa ; Corrigan, John D. ; Hammond, Flora ; Macciocchi, Stephen ; Ripley, David L. ; Sander, Angelle. / Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury. In: Archives of Physical Medicine and Rehabilitation. 2008 ; Vol. 89, No. 1. pp. 48-55.
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