Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury

Chad D. Vickery, Mark Sherer, Todd G. Nick, Risa Nakase-Richardson, John D. Corrigan, Flora Hammond, Stephen Macciocchi, David L. Ripley, Angelle Sander

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Vickery CD, Sherer M, Nick TG, Nakase-Richardson R, Corrigan JD, Hammond F, Macciocchi S, Ripley DL, Sander A. Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury. Objective: To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). Design: Prospective cohort study. Setting: Acute inpatient TBI rehabilitation. Participants: Participants were 1748 persons with TBI. Interventions: Not applicable. Main Outcome Measures: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. Results: Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. Conclusions: The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.

Original languageEnglish (US)
Pages (from-to)48-55
Number of pages8
JournalArchives of physical medicine and rehabilitation
Volume89
Issue number1
DOIs
StatePublished - Jan 1 2008
Externally publishedYes

Keywords

  • Alcoholic intoxication
  • Brain injuries
  • Rehabilitation
  • Treatment outcome

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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    Vickery, C. D., Sherer, M., Nick, T. G., Nakase-Richardson, R., Corrigan, J. D., Hammond, F., Macciocchi, S., Ripley, D. L., & Sander, A. (2008). Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury. Archives of physical medicine and rehabilitation, 89(1), 48-55. https://doi.org/10.1016/j.apmr.2007.07.047