Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury

Chad D. Vickery, Mark Sherer, Todd G. Nick, Risa Nakase-Richardson, John D. Corrigan, Flora Hammond, Stephen Macciocchi, David L. Ripley, Angelle Sander

30 Scopus citations

Abstract

Vickery CD, Sherer M, Nick TG, Nakase-Richardson R, Corrigan JD, Hammond F, Macciocchi S, Ripley DL, Sander A. Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury. Objective: To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). Design: Prospective cohort study. Setting: Acute inpatient TBI rehabilitation. Participants: Participants were 1748 persons with TBI. Interventions: Not applicable. Main Outcome Measures: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. Results: Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. Conclusions: The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.

Original languageEnglish (US)
Pages (from-to)48-55
Number of pages8
JournalArchives of physical medicine and rehabilitation
Volume89
Issue number1
DOIs
StatePublished - Jan 1 2008

Keywords

  • Alcoholic intoxication
  • Brain injuries
  • Rehabilitation
  • Treatment outcome

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

Cite this

Relationships Among Premorbid Alcohol Use, Acute Intoxication, and Early Functional Status After Traumatic Brain Injury. / Vickery, Chad D.; Sherer, Mark; Nick, Todd G.; Nakase-Richardson, Risa; Corrigan, John D.; Hammond, Flora; Macciocchi, Stephen; Ripley, David L.; Sander, Angelle.

In: Archives of physical medicine and rehabilitation, Vol. 89, No. 1, 01.01.2008, p. 48-55.

Research output: Contribution to journalArticle