Research in patients with heart failure: Challenges in recruitment

Susan J. Pressler, Usha Subramanian, Rose Mary Shaw, Leslie E. Meyer, Klarisa Stoudemire, Irmina Gradus-Pizlo

Research output: Contribution to journalArticle

15 Scopus citations


Background: Published studies of patients with heart failure may not include details about the challenges in the recruitment process. Objectives: To describe the recruitment process during the first 18 months of a study being conducted to evaluate cognitive deficits in patients with chronic heart failure. Methods: Details of the recruitment process are described for 2 clinic sites. Results: A total of 4027 echocardiograms were screened at site 1 to evaluate eligibility. Of the 161 patients eligible, 61 (38%) were invited to participate, and 29 of the 61 (48%) completed the study. At site 2, four hundred thirty-seven medical records of patients were screened, resulting in 163 eligible patients (37%). The staff invited 70 of the 163 patients (43%) to participate, and 52 of the 70 (74%) completed the study. The refusal rate was 23% at site 1 and 21% at site 2. Conclusions: Successful recruitment in studies involving patients with heart failure often requires screening of a large group of patients.

Original languageEnglish (US)
Pages (from-to)198-203
Number of pages6
JournalAmerican Journal of Critical Care
Issue number3
StatePublished - May 1 2008

ASJC Scopus subject areas

  • Critical Care

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    Pressler, S. J., Subramanian, U., Shaw, R. M., Meyer, L. E., Stoudemire, K., & Gradus-Pizlo, I. (2008). Research in patients with heart failure: Challenges in recruitment. American Journal of Critical Care, 17(3), 198-203.