Resected Adenocarcinoma of the Pancreas - 616 Patients: Results, Outcomes, and Prognostic Indicators

Taylor A. Sohn, Charles J. Yeo, John L. Cameron, Leonidas Koniaris, Sunjay Kaushal, Ross A. Abrams, Patricia K. Sauter, Joann Coleman, Ralph H. Hruban, Keith D. Lillemoe

Research output: Contribution to journalArticle

1187 Citations (Scopus)

Abstract

This large-volume, single-institution review examines factors influencing long-term survival after resection in patients with adenocarcinoma of the head, neck, uncinate process, body, or tail of the pancreas. Between January 1984 and July 1999 inclusive, 616 patients with adenocarcinoma of the pancreas underwent surgical resection. A retrospective analysis of a prospectively collected database was performed. Both univariate and multivariate models were used to determine the factors influencing survival. Of the 616 patients, 526 (85%) underwent pancreaticoduodenectomy for adenocarcinoma of the head, neck, or uncinate process of the pancreas, 52 (9%) underwent distal pancreatectomy for adenocarcinoma of the body or tail, and 38 (6%) underwent total pancreatectomy for adenocarcinoma extensively involving the gland. The mean age of the patients was 64.3 years, with 54% being male and 91% being white. The overall perioperative mortality rate was 2.3%, whereas the incidence of postoperative complications was 30%. The median postoperative length of stay was 11 days. The mean tumor diameter was 3.2 cm, with 72% of patients having positive lymph nodes, 30% having positive resection margins, and 36% having poorly differentiated tumors. Patients undergoing distal pancreatectomy for left-sided lesions had larger tumors (4.7 vs. 3.1 cm, P

Original languageEnglish (US)
Pages (from-to)567-579
Number of pages13
JournalJournal of Gastrointestinal Surgery
Volume4
Issue number6
StatePublished - Nov 2000
Externally publishedYes

Fingerprint

Pancreas
Adenocarcinoma
Pancreatectomy
Neck
Head
Neoplasms
Pancreaticoduodenectomy
Survival
Length of Stay
Lymph Nodes
Databases
Mortality
Incidence

Keywords

  • Adenocarcinoma
  • Pancreatic cancer
  • Prognostic factors
  • Survival

ASJC Scopus subject areas

  • Surgery

Cite this

Sohn, T. A., Yeo, C. J., Cameron, J. L., Koniaris, L., Kaushal, S., Abrams, R. A., ... Lillemoe, K. D. (2000). Resected Adenocarcinoma of the Pancreas - 616 Patients: Results, Outcomes, and Prognostic Indicators. Journal of Gastrointestinal Surgery, 4(6), 567-579.

Resected Adenocarcinoma of the Pancreas - 616 Patients : Results, Outcomes, and Prognostic Indicators. / Sohn, Taylor A.; Yeo, Charles J.; Cameron, John L.; Koniaris, Leonidas; Kaushal, Sunjay; Abrams, Ross A.; Sauter, Patricia K.; Coleman, Joann; Hruban, Ralph H.; Lillemoe, Keith D.

In: Journal of Gastrointestinal Surgery, Vol. 4, No. 6, 11.2000, p. 567-579.

Research output: Contribution to journalArticle

Sohn, TA, Yeo, CJ, Cameron, JL, Koniaris, L, Kaushal, S, Abrams, RA, Sauter, PK, Coleman, J, Hruban, RH & Lillemoe, KD 2000, 'Resected Adenocarcinoma of the Pancreas - 616 Patients: Results, Outcomes, and Prognostic Indicators', Journal of Gastrointestinal Surgery, vol. 4, no. 6, pp. 567-579.
Sohn, Taylor A. ; Yeo, Charles J. ; Cameron, John L. ; Koniaris, Leonidas ; Kaushal, Sunjay ; Abrams, Ross A. ; Sauter, Patricia K. ; Coleman, Joann ; Hruban, Ralph H. ; Lillemoe, Keith D. / Resected Adenocarcinoma of the Pancreas - 616 Patients : Results, Outcomes, and Prognostic Indicators. In: Journal of Gastrointestinal Surgery. 2000 ; Vol. 4, No. 6. pp. 567-579.
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