Results of therapy in adult acute lymphocytic leukemia

L. H. Einhorn, S. Meyer, W. H. Bond, R. J. Rohn

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

27 Adult patients with acute lymphocyte leukemia have been analyzed. Complete remission was induced in 9 of 13 patients treated with prednisone + 6 MP, 4 of 6 patients treated with prednisone + vincristine, and the one patient treated with a combination of prednisone, vincristine, 6 MP, and methotrexate. The median survival for these 20 patients was 11 months and the median duration of complete remission was 7 1/2 months. Two of these patients remain in complete remission at 8+ years. Our most recent regimen for remission induction, prednisone + vincristine + daunomycin, has produced complete remission in 7 of 7 patients, with a median duration of complete remission of 15 months. Three patients remain in their original complete remission from 16+ to 24+ months, and 5 of these 7 patients remain alive from 16+ to 24+ months.

Original languageEnglish (US)
Pages (from-to)214-220
Number of pages7
JournalONCOLOGY
Volume32
Issue number5-6
DOIs
StatePublished - Jan 1 1975

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Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prednisone
Vincristine
Therapeutics
Remission Induction
Daunorubicin
Methotrexate
Leukemia
Lymphocytes
Survival

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Results of therapy in adult acute lymphocytic leukemia. / Einhorn, L. H.; Meyer, S.; Bond, W. H.; Rohn, R. J.

In: ONCOLOGY, Vol. 32, No. 5-6, 01.01.1975, p. 214-220.

Research output: Contribution to journalArticle

Einhorn, LH, Meyer, S, Bond, WH & Rohn, RJ 1975, 'Results of therapy in adult acute lymphocytic leukemia', ONCOLOGY, vol. 32, no. 5-6, pp. 214-220. https://doi.org/10.1159/000225071
Einhorn, L. H. ; Meyer, S. ; Bond, W. H. ; Rohn, R. J. / Results of therapy in adult acute lymphocytic leukemia. In: ONCOLOGY. 1975 ; Vol. 32, No. 5-6. pp. 214-220.
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