Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

David D. Bowtell, Steffen Böhm, Ahmed A. Ahmed, Paul Joseph Aspuria, Robert C. Bast, Valerie Beral, Jonathan S. Berek, Michael J. Birrer, Sarah Blagden, Michael A. Bookman, James D. Brenton, Katherine B. Chiappinelli, Filipe Correia Martins, George Coukos, Ronny Drapkin, Richard Edmondson, Christina Fotopoulou, Hani Gabra, Jérôme Galon, Charlie GourleyValerie Heong, David G. Huntsman, Marcin Iwanicki, Beth Y. Karlan, Allyson Kaye, Ernst Lengyel, Douglas A. Levine, Karen H. Lu, Iain A. McNeish, Usha Menon, Steven A. Narod, Brad H. Nelson, Kenneth P. Nephew, Paul Pharoah, Daniel J. Powell, Pilar Ramos, Iris L. Romero, Clare L. Scott, Anil K. Sood, Euan A. Stronach, Frances R. Balkwill

Research output: Contribution to journalReview article

338 Scopus citations

Abstract

High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of ovarian cancer deaths, and overall survival has not changed significantly for several decades. In this Opinion article, we outline a set of research priorities that we believe will reduce incidence and improve outcomes for women with this disease. This 'roadmap' for HGSOC was determined after extensive discussions at an Ovarian Cancer Action meeting in January 2015.

Original languageEnglish (US)
Pages (from-to)668-679
Number of pages12
JournalNature Reviews Cancer
Volume15
Issue number11
DOIs
StatePublished - Oct 23 2015

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Bowtell, D. D., Böhm, S., Ahmed, A. A., Aspuria, P. J., Bast, R. C., Beral, V., Berek, J. S., Birrer, M. J., Blagden, S., Bookman, M. A., Brenton, J. D., Chiappinelli, K. B., Martins, F. C., Coukos, G., Drapkin, R., Edmondson, R., Fotopoulou, C., Gabra, H., Galon, J., ... Balkwill, F. R. (2015). Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer. Nature Reviews Cancer, 15(11), 668-679. https://doi.org/10.1038/nrc4019