Retinal blood flow indices in patients infected with human immunodeficiency virus

Chi Wah Yung, Alon Harris, Stephen Massicotte, George Chioran, Gabriel Krombach, Ronald Danis, Sebastian Wolf

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Aims/background - Abnormal blood flow dynamics are believed to contribute to the development of retinal microvascular disease in patients infected with human immunodeficiency virus (HIV). In this study, the scanning laser ophthalmoscope (SLO) was used, combined with fluorescein angiography, to measure retinal blood flow indices in HIV seropositive patients. Methods - Arteriovenous passage time (AVP) and perifoveal capillary blood flow velocity (CFV) were measured in 23 HIV infected patients and 23 control subjects with SLO fluorescein angiography. Results - No significant difference in AVP was found between the two groups. However, CFV was significantly reduced in HIV infected patients (p = 0.013). Conclusion - Patients infected with HIV show abnormal haemodynamics at the level of the perifoveal capillaries.

Original languageEnglish (US)
Pages (from-to)723-727
Number of pages5
JournalBritish Journal of Ophthalmology
Volume80
Issue number8
DOIs
StatePublished - Aug 1996

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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