Retinal thickness estimation from SD-OCT macular scans

N. Hammes, L. Racette, B. C. Samuels, G. Tsechpenakis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Glaucoma, a leading cause of blindness worldwide, can be detected using retinal thicknesses from spectral-domain optical coherence tomography (SD-OCT) scans of the macula. We calculate the desired thickness maps as the distance between the inner-limiting membrane (ILM) and retinal pigmented epithelium (RPE) of the retina. To delineate these two layers, we use a set of two deformable open surfaces that are driven by intensity contrast, while preserving their shape and topology properties, i.e. local surface smoothness and inter-surface distance smoothness. To evaluate our method, qualified graders manually segmented 30 random sections from 20 OCT image stacks, in triplicate; we make comparisons with obtained ground-truth and the clinically tested Heidelberg Spectralis segmentation. We show the superiority of our method with respect to accuracy and average execution time (∼7 secs), validating it as a clinical tool.

Original languageEnglish (US)
Title of host publication2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015
PublisherIEEE Computer Society
Pages213-217
Number of pages5
ISBN (Electronic)9781479923748
DOIs
StatePublished - Jul 21 2015
Event12th IEEE International Symposium on Biomedical Imaging, ISBI 2015 - Brooklyn, United States
Duration: Apr 16 2015Apr 19 2015

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2015-July
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other12th IEEE International Symposium on Biomedical Imaging, ISBI 2015
CountryUnited States
CityBrooklyn
Period4/16/154/19/15

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Keywords

  • Retinal thickness
  • early detection of glaucoma
  • interacting deformable surfaces

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Hammes, N., Racette, L., Samuels, B. C., & Tsechpenakis, G. (2015). Retinal thickness estimation from SD-OCT macular scans. In 2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015 (pp. 213-217). [7163852] (Proceedings - International Symposium on Biomedical Imaging; Vol. 2015-July). IEEE Computer Society. https://doi.org/10.1109/ISBI.2015.7163852