Retrobulbar hemodynamics in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure

Yuji Kondo, Yoshiaki Niwa, Tetsuya Yamamoto, Akira Sawada, Alon Harris, Yoshiaki Kitazawa

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

PURPOSE: To investigate retrobulbar hemodynamics by means of color Doppler imaging in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure. METHODS: Forty-nine consecutive patients who met the enrollment criteria were enrolled in a prospective study. We measured intraocular pressure at 2-hour intervals for 24 hours and performed color Doppler imaging of the orbital arteries, 48-hour ambulatory blood pressure monitoring, and visual field testing. Color Doppler parameters were compared between subjects with higher ocular perfusion pressure in the eye that had a better mean deviation (concordant group) and worse mean deviation (discordant group). RESULTS: In the eyes with the better mean deviation, the end-diastolic velocity of the ophthalmic artery was significantly slower in the discordant group (P=.0145), while in the eyes with the worse mean deviation, the peak systolic and end-diastolic velocities of the ophthalmic artery were significantly slower and the resistance index of the ophthalmic artery was significantly higher in the discordant group (P=.0395, P=.0088, and P=.0324, respectively). In the concordant group, the end-diastolic velocity of the central retinal artery was slower in eyes with a worse mean deviation. CONCLUSION: Retrobulbar hemodynamics are significantly altered in patients with normal-tension glaucoma who have better ocular perfusion pressure in the eye that has a worse mean deviation. (C) 2000 by Elsevier Science Inc.

Original languageEnglish
Pages (from-to)454-460
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume130
Issue number4
DOIs
StatePublished - Oct 2000

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Low Tension Glaucoma
Visual Fields
Perfusion
Hemodynamics
Pressure
Ophthalmic Artery
Color
Retinal Artery
Ambulatory Blood Pressure Monitoring
Intraocular Pressure
Arteries
Prospective Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Retrobulbar hemodynamics in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure. / Kondo, Yuji; Niwa, Yoshiaki; Yamamoto, Tetsuya; Sawada, Akira; Harris, Alon; Kitazawa, Yoshiaki.

In: American Journal of Ophthalmology, Vol. 130, No. 4, 10.2000, p. 454-460.

Research output: Contribution to journalArticle

Kondo, Yuji ; Niwa, Yoshiaki ; Yamamoto, Tetsuya ; Sawada, Akira ; Harris, Alon ; Kitazawa, Yoshiaki. / Retrobulbar hemodynamics in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure. In: American Journal of Ophthalmology. 2000 ; Vol. 130, No. 4. pp. 454-460.
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