Review article: Registered nurse-administered propofol sedation for endoscopy

S. C. Chen, Douglas Rex

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Propofol has several attractive properties that render it a potential alternative sedative agent for endoscopy. Compared with meperidine and midazolam, it has an ultra-short onset of action, short plasma half-life, short time to achieve sedation, faster time to recovery and discharge, and results in higher patient satisfaction. Shorter times to achieve sedation enhance efficiency in the endoscopy unit. Multiple studies have documented the safe administration of propofol by non-anaesthesiologists. Administration by registered nurses is more cost-effective than administration by anaesthesiologists. However, the administration of propofol by a registered nurse supervised only by the endoscopist is controversial because the drug has the potential to produce sudden and severe respiratory depression. More information is needed on how training nurses and endoscopists should proceed to give propofol, as well as the optimal level of monitoring to ensure the safety of nurse-administered propofol.

Original languageEnglish
Pages (from-to)147-155
Number of pages9
JournalAlimentary Pharmacology and Therapeutics
Volume19
Issue number2
DOIs
StatePublished - Jan 15 2004

Fingerprint

Propofol
Endoscopy
Nurses
Meperidine
Midazolam
Hypnotics and Sedatives
Patient Satisfaction
Respiratory Insufficiency
Half-Life
Safety
Costs and Cost Analysis
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Review article : Registered nurse-administered propofol sedation for endoscopy. / Chen, S. C.; Rex, Douglas.

In: Alimentary Pharmacology and Therapeutics, Vol. 19, No. 2, 15.01.2004, p. 147-155.

Research output: Contribution to journalArticle

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