Reviewing the Evidence that Polypectomy Prevents Cancer

Research output: Contribution to journalReview article

Abstract

Colonoscopic polypectomy is fundamental to effective prevention of colorectal cancer. Polypectomy reduces colorectal cancer incidence and mortality by altering the natural history and progression of precancerous precursor polyps. Epidemiologic data from the United States, where colorectal cancer rates have been steadily declining in parallel with screening efforts, provide indisputable evidence about the effectiveness of polypectomy. Randomized controlled trials of fecal occult blood tests and flexible sigmoidoscopy, and observational colonoscopy studies, provide additional support. Longitudinal studies have shown variable levels of protection after polypectomy, highlighting the central importance of high quality and adequate surveillance of higher-risk patients.

Original languageEnglish (US)
JournalGastrointestinal Endoscopy Clinics of North America
DOIs
StatePublished - Jan 1 2019

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Colorectal Neoplasms
Sigmoidoscopy
Neoplasms
Occult Blood
Hematologic Tests
Colonoscopy
Polyps
Natural History
Observational Studies
Longitudinal Studies
Randomized Controlled Trials
Mortality
Incidence

Keywords

  • Colonoscopy
  • Colorectal neoplasms
  • Polypectomy
  • Prevention

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Reviewing the Evidence that Polypectomy Prevents Cancer. / Kahi, Charles.

In: Gastrointestinal Endoscopy Clinics of North America, 01.01.2019.

Research output: Contribution to journalReview article

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AB - Colonoscopic polypectomy is fundamental to effective prevention of colorectal cancer. Polypectomy reduces colorectal cancer incidence and mortality by altering the natural history and progression of precancerous precursor polyps. Epidemiologic data from the United States, where colorectal cancer rates have been steadily declining in parallel with screening efforts, provide indisputable evidence about the effectiveness of polypectomy. Randomized controlled trials of fecal occult blood tests and flexible sigmoidoscopy, and observational colonoscopy studies, provide additional support. Longitudinal studies have shown variable levels of protection after polypectomy, highlighting the central importance of high quality and adequate surveillance of higher-risk patients.

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