Ribose-modified mizoribine analogues: Synthesis and biological evaluation

Palmarisa Franchetti, Michela Pasqualini, Loredana Cappellacci, Riccardo Petrelli, Patrizia Vita, Mario Grifantini, Hiremagalur N. Jayaram

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

□ Synthesis, conformational analysis and antitumor evaluation of 2′- and 3′-C-methyl analogues of mizoribine (bredinine, 4-carbamoyl-1-β-D-ribofuranosylimidazole-5-olate) are reported.

Original languageEnglish
Pages (from-to)2023-2027
Number of pages5
JournalNucleosides, Nucleotides and Nucleic Acids
Volume24
Issue number10-12
DOIs
StatePublished - Sep 1 2005

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Ribose
bredinin

Keywords

  • Antitumor agents
  • IMPDH inhibitors
  • Mizoribine analogues

ASJC Scopus subject areas

  • Genetics
  • Biochemistry

Cite this

Franchetti, P., Pasqualini, M., Cappellacci, L., Petrelli, R., Vita, P., Grifantini, M., & Jayaram, H. N. (2005). Ribose-modified mizoribine analogues: Synthesis and biological evaluation. Nucleosides, Nucleotides and Nucleic Acids, 24(10-12), 2023-2027. https://doi.org/10.1080/15257770500334673

Ribose-modified mizoribine analogues : Synthesis and biological evaluation. / Franchetti, Palmarisa; Pasqualini, Michela; Cappellacci, Loredana; Petrelli, Riccardo; Vita, Patrizia; Grifantini, Mario; Jayaram, Hiremagalur N.

In: Nucleosides, Nucleotides and Nucleic Acids, Vol. 24, No. 10-12, 01.09.2005, p. 2023-2027.

Research output: Contribution to journalArticle

Franchetti, P, Pasqualini, M, Cappellacci, L, Petrelli, R, Vita, P, Grifantini, M & Jayaram, HN 2005, 'Ribose-modified mizoribine analogues: Synthesis and biological evaluation', Nucleosides, Nucleotides and Nucleic Acids, vol. 24, no. 10-12, pp. 2023-2027. https://doi.org/10.1080/15257770500334673
Franchetti P, Pasqualini M, Cappellacci L, Petrelli R, Vita P, Grifantini M et al. Ribose-modified mizoribine analogues: Synthesis and biological evaluation. Nucleosides, Nucleotides and Nucleic Acids. 2005 Sep 1;24(10-12):2023-2027. https://doi.org/10.1080/15257770500334673
Franchetti, Palmarisa ; Pasqualini, Michela ; Cappellacci, Loredana ; Petrelli, Riccardo ; Vita, Patrizia ; Grifantini, Mario ; Jayaram, Hiremagalur N. / Ribose-modified mizoribine analogues : Synthesis and biological evaluation. In: Nucleosides, Nucleotides and Nucleic Acids. 2005 ; Vol. 24, No. 10-12. pp. 2023-2027.
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