Right heart failure

Anthony R. Cucci, Mohammed Hadi, Tim Lahm

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Right ventricular failure (RVF) is a frequent and formidable clinical challenge in the intensive care unit, the operating room, the general ward, and the outpatient setting. The presence of RVF (1) carries substantial morbidity and mortality and (2) complicates the use of commonly employed treatment strategies in both inpatients and outpatients. In contrast to the left ventricle (LV), the right ventricle (RV) remains relatively understudied, and none of the major professional societies have published any guidelines on how to approach patients with RVF. Due to embryological, anatomical, physiological, biochemical, and electrophysiological differences between the RV and LV, paradigms that are important for the treatment of the failing LV cannot be extrapolated to RVF. However, with pulmonary hypertension (PH) having become a major area of scientific and clinical interest, recent studies have shed more light on the physiology of the normal RV and the pathophysiology of its failure. Using a comprehensive and evidence-based approach, this chapter will (1) highlight the pathophysiology of the failing RV; (2) discuss the etiologies of acute, chronic, and acute-on-chronic RVF; (3) describe invasive and noninvasive approaches that assist in diagnosis and risk stratification; and (4) emphasize treatment strategies for stable (chronic) and decompensated (acute) RVF.

Original languageEnglish (US)
Title of host publicationEvidence-Based Cardiology Consult
PublisherSpringer-Verlag London Ltd
Pages311-329
Number of pages19
ISBN (Print)9781447144410, 1447144406, 9781447144403
DOIs
StatePublished - Nov 1 2013

Fingerprint

Heart Ventricles
Heart Failure
Outpatients
Patients' Rooms
Patient Rights
Operating Rooms
Pulmonary Hypertension
Intensive Care Units
Inpatients
Therapeutics
Guidelines
Morbidity
Mortality

Keywords

  • Afterload
  • Cardiogenic shock
  • Contractility
  • Diuretics
  • Heart failure
  • Inotropic therapy
  • Preload
  • Pulmonary embolism
  • Pulmonary hypertension
  • Pulmonary vasodilators

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cucci, A. R., Hadi, M., & Lahm, T. (2013). Right heart failure. In Evidence-Based Cardiology Consult (pp. 311-329). Springer-Verlag London Ltd. https://doi.org/10.1007/978-1-4471-4441-0_22

Right heart failure. / Cucci, Anthony R.; Hadi, Mohammed; Lahm, Tim.

Evidence-Based Cardiology Consult. Springer-Verlag London Ltd, 2013. p. 311-329.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cucci, AR, Hadi, M & Lahm, T 2013, Right heart failure. in Evidence-Based Cardiology Consult. Springer-Verlag London Ltd, pp. 311-329. https://doi.org/10.1007/978-1-4471-4441-0_22
Cucci AR, Hadi M, Lahm T. Right heart failure. In Evidence-Based Cardiology Consult. Springer-Verlag London Ltd. 2013. p. 311-329 https://doi.org/10.1007/978-1-4471-4441-0_22
Cucci, Anthony R. ; Hadi, Mohammed ; Lahm, Tim. / Right heart failure. Evidence-Based Cardiology Consult. Springer-Verlag London Ltd, 2013. pp. 311-329
@inbook{cecf52a64e9d4d28a0e7fe7c3a2f243d,
title = "Right heart failure",
abstract = "Right ventricular failure (RVF) is a frequent and formidable clinical challenge in the intensive care unit, the operating room, the general ward, and the outpatient setting. The presence of RVF (1) carries substantial morbidity and mortality and (2) complicates the use of commonly employed treatment strategies in both inpatients and outpatients. In contrast to the left ventricle (LV), the right ventricle (RV) remains relatively understudied, and none of the major professional societies have published any guidelines on how to approach patients with RVF. Due to embryological, anatomical, physiological, biochemical, and electrophysiological differences between the RV and LV, paradigms that are important for the treatment of the failing LV cannot be extrapolated to RVF. However, with pulmonary hypertension (PH) having become a major area of scientific and clinical interest, recent studies have shed more light on the physiology of the normal RV and the pathophysiology of its failure. Using a comprehensive and evidence-based approach, this chapter will (1) highlight the pathophysiology of the failing RV; (2) discuss the etiologies of acute, chronic, and acute-on-chronic RVF; (3) describe invasive and noninvasive approaches that assist in diagnosis and risk stratification; and (4) emphasize treatment strategies for stable (chronic) and decompensated (acute) RVF.",
keywords = "Afterload, Cardiogenic shock, Contractility, Diuretics, Heart failure, Inotropic therapy, Preload, Pulmonary embolism, Pulmonary hypertension, Pulmonary vasodilators",
author = "Cucci, {Anthony R.} and Mohammed Hadi and Tim Lahm",
year = "2013",
month = "11",
day = "1",
doi = "10.1007/978-1-4471-4441-0_22",
language = "English (US)",
isbn = "9781447144410",
pages = "311--329",
booktitle = "Evidence-Based Cardiology Consult",
publisher = "Springer-Verlag London Ltd",

}

TY - CHAP

T1 - Right heart failure

AU - Cucci, Anthony R.

AU - Hadi, Mohammed

AU - Lahm, Tim

PY - 2013/11/1

Y1 - 2013/11/1

N2 - Right ventricular failure (RVF) is a frequent and formidable clinical challenge in the intensive care unit, the operating room, the general ward, and the outpatient setting. The presence of RVF (1) carries substantial morbidity and mortality and (2) complicates the use of commonly employed treatment strategies in both inpatients and outpatients. In contrast to the left ventricle (LV), the right ventricle (RV) remains relatively understudied, and none of the major professional societies have published any guidelines on how to approach patients with RVF. Due to embryological, anatomical, physiological, biochemical, and electrophysiological differences between the RV and LV, paradigms that are important for the treatment of the failing LV cannot be extrapolated to RVF. However, with pulmonary hypertension (PH) having become a major area of scientific and clinical interest, recent studies have shed more light on the physiology of the normal RV and the pathophysiology of its failure. Using a comprehensive and evidence-based approach, this chapter will (1) highlight the pathophysiology of the failing RV; (2) discuss the etiologies of acute, chronic, and acute-on-chronic RVF; (3) describe invasive and noninvasive approaches that assist in diagnosis and risk stratification; and (4) emphasize treatment strategies for stable (chronic) and decompensated (acute) RVF.

AB - Right ventricular failure (RVF) is a frequent and formidable clinical challenge in the intensive care unit, the operating room, the general ward, and the outpatient setting. The presence of RVF (1) carries substantial morbidity and mortality and (2) complicates the use of commonly employed treatment strategies in both inpatients and outpatients. In contrast to the left ventricle (LV), the right ventricle (RV) remains relatively understudied, and none of the major professional societies have published any guidelines on how to approach patients with RVF. Due to embryological, anatomical, physiological, biochemical, and electrophysiological differences between the RV and LV, paradigms that are important for the treatment of the failing LV cannot be extrapolated to RVF. However, with pulmonary hypertension (PH) having become a major area of scientific and clinical interest, recent studies have shed more light on the physiology of the normal RV and the pathophysiology of its failure. Using a comprehensive and evidence-based approach, this chapter will (1) highlight the pathophysiology of the failing RV; (2) discuss the etiologies of acute, chronic, and acute-on-chronic RVF; (3) describe invasive and noninvasive approaches that assist in diagnosis and risk stratification; and (4) emphasize treatment strategies for stable (chronic) and decompensated (acute) RVF.

KW - Afterload

KW - Cardiogenic shock

KW - Contractility

KW - Diuretics

KW - Heart failure

KW - Inotropic therapy

KW - Preload

KW - Pulmonary embolism

KW - Pulmonary hypertension

KW - Pulmonary vasodilators

UR - http://www.scopus.com/inward/record.url?scp=84928930011&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928930011&partnerID=8YFLogxK

U2 - 10.1007/978-1-4471-4441-0_22

DO - 10.1007/978-1-4471-4441-0_22

M3 - Chapter

AN - SCOPUS:84949179171

SN - 9781447144410

SN - 1447144406

SN - 9781447144403

SP - 311

EP - 329

BT - Evidence-Based Cardiology Consult

PB - Springer-Verlag London Ltd

ER -