Right ventricular systolic function in adolescents and young adults after mustard operation for transposition of the great arteries

R. A. Hurwitz, R. L. Caldwell, D. A. Girod, John Brown

Research output: Contribution to journalArticle

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Abstract

This study evaluates long-term (>10 years since surgery) right ventricular (RV) systolic function in patients who had previously undergone intraatrial baffle surgery for transposition of the great arteries. Studies suggest these patients are clinically stable and lead satisfactory lifestyles, but long- term ventricular performance is not known. Radionuclide angiocardiography was used to estimate RV ejection fraction in 58 patients a mean of 14 years after the Mustard operation. Repeat studies were performed in 32 patients. The absolute RV ejection fraction of 0.53 ± 0.10 in our patients did not differ from normal values. Nine patients had a value <0.42, placing them >2 SDs below normal. Repeat RV ejection fraction decreased from 0.54 ± 0.11 to 0.51 ± 0.11 (p <0.1) in 32 patients, and >0.10 in 6. Thus, RV ejection fraction was abnormal in 9 of 58 patients (16%) evaluated >10 years after a Mustard operation. Repeat studies demonstrate worsening in at least 6 of 32 patients (19%). These postoperative Mustard patients require continued evaluation, even in the absence of overt symptomatology.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalThe American Journal of Cardiology
Volume77
Issue number4
DOIs
StatePublished - 1996

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Right Ventricular Function
Transposition of Great Vessels
Young Adult
Stroke Volume
Angiocardiography
Arterial Switch Operation
Mustard Plant
Radioisotopes
Life Style
Reference Values

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Right ventricular systolic function in adolescents and young adults after mustard operation for transposition of the great arteries. / Hurwitz, R. A.; Caldwell, R. L.; Girod, D. A.; Brown, John.

In: The American Journal of Cardiology, Vol. 77, No. 4, 1996, p. 294-297.

Research output: Contribution to journalArticle

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