Risk factors in calcium stone disease of the urinary tract

W. G. Robertson, Munro Peacock, P. J. Heyburn, D. H. Marshall, P. B. Clark

Research output: Contribution to journalArticle

229 Citations (Scopus)

Abstract

The concept that calcium stone formation may be explained on the basis of a number of risk factors is developed. The main risk factors involved are shown to be calcium, oxalate, pH, acid mucopolysaccharides and uric acid. A method is described for calculating and combining the individual risk factors into a measure of the 'relative probability' of forming stones (P(SF)). P(SF) values are generally lower in normal subjects than in stone-formers. Amongst the normals, P(SF) values are lower in children and women than in men. Recurrent stone-formers have the highest P(SF) values and these correlate well with the severity of the disease as defined by the stone episode rate of the patient. Single stone-formers have P(SF) values intermediate between those of normal men and those of recurrent stone-formers.

Original languageEnglish (US)
Pages (from-to)449-454
Number of pages6
JournalBritish Journal of Urology
Volume50
Issue number7
StatePublished - 1978
Externally publishedYes

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Urologic Diseases
Urinary Calculi
Calcium
Calcium Oxalate
Glycosaminoglycans
Uric Acid
Acids

ASJC Scopus subject areas

  • Urology

Cite this

Robertson, W. G., Peacock, M., Heyburn, P. J., Marshall, D. H., & Clark, P. B. (1978). Risk factors in calcium stone disease of the urinary tract. British Journal of Urology, 50(7), 449-454.

Risk factors in calcium stone disease of the urinary tract. / Robertson, W. G.; Peacock, Munro; Heyburn, P. J.; Marshall, D. H.; Clark, P. B.

In: British Journal of Urology, Vol. 50, No. 7, 1978, p. 449-454.

Research output: Contribution to journalArticle

Robertson, WG, Peacock, M, Heyburn, PJ, Marshall, DH & Clark, PB 1978, 'Risk factors in calcium stone disease of the urinary tract', British Journal of Urology, vol. 50, no. 7, pp. 449-454.
Robertson WG, Peacock M, Heyburn PJ, Marshall DH, Clark PB. Risk factors in calcium stone disease of the urinary tract. British Journal of Urology. 1978;50(7):449-454.
Robertson, W. G. ; Peacock, Munro ; Heyburn, P. J. ; Marshall, D. H. ; Clark, P. B. / Risk factors in calcium stone disease of the urinary tract. In: British Journal of Urology. 1978 ; Vol. 50, No. 7. pp. 449-454.
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