Risk perceptions after human papillomavirus vaccination in HIV-infected adolescents and young adult women

Jessica A. Kahn, Jiahong Xu, Gregory Zimet, Nancy Liu, René Gonin, Mary E. Dillard, Kathleen Squires

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Purpose: To examine risk perceptions (perceived risk of human papillomavirus [HPV], perceived risk of other sexually transmitted infections [STIs], and need for safer sexual behaviors) and to determine factors associated with these risk perceptions after HPV vaccination. Methods: Data were collected at the baseline visit of an HPV-6, -11, -16, -18 vaccine clinical trial in 16-23-year-old HIV-infected young women (N = 99). Immediately after receiving the first vaccine dose, participants completed a confidential questionnaire that included three 5-item scales measuring perceived risk of HPV, perceived risk of other STIs, and need for safer sexual behaviors. Linear and logistic regression models were used to examine associations between baseline characteristics (demographic characteristics; cluster of differentiation antigen 4 (CD4 +) count; HIV viral load; knowledge about HPV and HPV vaccines; sexual behaviors; and STI diagnosis) and each measure of risk perceptions. Results: Most participants perceived themselves to be at lower risk for HPV (mean scale score = 19.5/50), most perceived that they were not at lower risk for other STIs (mean = 31.2/50), and the vast majority reported that there was still a need for safer sexual behaviors after vaccination (mean = 43.1/50). Multivariate analyses indicated that knowledge about HPV and HPV vaccines was associated with perceived need for safer sexual behaviors (OR = 1.05, 95% CI = 1.0-1.1). Conclusions: Although almost all young women in this study believed that safer sexual behaviors were still important after HPV vaccination, a subset believed they were at less risk for STIs other than HPV. Educational interventions are needed to prevent misperceptions and promote healthy behaviors after vaccination.

Original languageEnglish
Pages (from-to)464-470
Number of pages7
JournalJournal of Adolescent Health
Volume50
Issue number5
DOIs
StatePublished - May 2012

Fingerprint

Young Adult
Vaccination
HIV
Sexual Behavior
Sexually Transmitted Diseases
Papillomavirus Vaccines
Vaccines
Logistic Models
CD Antigens
Human papillomavirus 11
Human papillomavirus 6
CD4 Lymphocyte Count
Viral Load
Linear Models
Multivariate Analysis
Demography
Clinical Trials

Keywords

  • Adolescent
  • HIV
  • Human papillomavirus
  • Risk perceptions
  • Vaccine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health
  • Public Health, Environmental and Occupational Health

Cite this

Risk perceptions after human papillomavirus vaccination in HIV-infected adolescents and young adult women. / Kahn, Jessica A.; Xu, Jiahong; Zimet, Gregory; Liu, Nancy; Gonin, René; Dillard, Mary E.; Squires, Kathleen.

In: Journal of Adolescent Health, Vol. 50, No. 5, 05.2012, p. 464-470.

Research output: Contribution to journalArticle

Kahn, Jessica A. ; Xu, Jiahong ; Zimet, Gregory ; Liu, Nancy ; Gonin, René ; Dillard, Mary E. ; Squires, Kathleen. / Risk perceptions after human papillomavirus vaccination in HIV-infected adolescents and young adult women. In: Journal of Adolescent Health. 2012 ; Vol. 50, No. 5. pp. 464-470.
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