Risperidone in pervasive developmental disorders

Craig A. Erickson, Kimberly A. Stigler, David J. Posey, Christopher J. McDougle

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Atypical antipsychotics are increasingly used in the treatment of severe behavioral I disturbances in people with pervasive developmental disorders. Among these compounds, risperidone has been the most broadly studied. This drug profile will review the available data on the use of risperidone in individuals with pervasive developmental disorders. In addition, the chemistry, pharmacokinetics, pharmacodynamics and metabolism of risperidone are discussed. Emphasis will be placed on adverse effects associated with risperidone in these people, including a discussion of measures that can be taken to monitor for these effects. Finally, a discussion of the future direction of risperidone use in this population and key issues will be presented.

Original languageEnglish
Pages (from-to)713-719
Number of pages7
JournalExpert Review of Neurotherapeutics
Volume5
Issue number6
DOIs
StatePublished - Nov 2005

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Risperidone
Antipsychotic Agents
Pharmacokinetics
Pharmaceutical Preparations
Population

Keywords

  • Aggression
  • Autism
  • Pervasive developmental disorder
  • Risperidone
  • Self-injurious behavior

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Erickson, C. A., Stigler, K. A., Posey, D. J., & McDougle, C. J. (2005). Risperidone in pervasive developmental disorders. Expert Review of Neurotherapeutics, 5(6), 713-719. https://doi.org/10.1586/14737175.5.6.713

Risperidone in pervasive developmental disorders. / Erickson, Craig A.; Stigler, Kimberly A.; Posey, David J.; McDougle, Christopher J.

In: Expert Review of Neurotherapeutics, Vol. 5, No. 6, 11.2005, p. 713-719.

Research output: Contribution to journalArticle

Erickson, CA, Stigler, KA, Posey, DJ & McDougle, CJ 2005, 'Risperidone in pervasive developmental disorders', Expert Review of Neurotherapeutics, vol. 5, no. 6, pp. 713-719. https://doi.org/10.1586/14737175.5.6.713
Erickson, Craig A. ; Stigler, Kimberly A. ; Posey, David J. ; McDougle, Christopher J. / Risperidone in pervasive developmental disorders. In: Expert Review of Neurotherapeutics. 2005 ; Vol. 5, No. 6. pp. 713-719.
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