Role of hepatic macrophages in alcoholic liver disease

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Alcohol consumption can lead to the increase in gut permeability and cause the translocation of bacteriaderived lipopolysaccharides from the gut to the liver, which subsequently activates immune responses. In this process, macrophages play a critical role and involve in the pathogenesis of alcoholic liver disease (ALD). To define the mechanism underpinning the function of macrophages, it is important to conduct extensive studies to further explicate the phenotypic diversity of macrophages in the context of ALD. In this review, the role of hepatic macrophages in the pathogenesis of ALD is discussed.

Original languageEnglish (US)
Pages (from-to)1075-1077
Number of pages3
JournalJournal of Investigative Medicine
Volume64
Issue number6
DOIs
StatePublished - Aug 1 2016

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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