Role of Octreotide in Pediatric Gastrointestinal Bleeding Secondary to Angiodysplasia in Children with Right Heart Failure

Kanika Puri, Robert Caldwell, Jean Molleston

Research output: Contribution to journalArticle

Abstract

OBJECTIVES:: Angiodysplasia is a relatively uncommon cause of GI bleeding in children and may be seen in right heart failure. Octreotide has been used successfully in adult patients with gastrointestinal bleeding due to angiodysplasias. METHODS:: We describe two patients who had congenital heart disease with right heart failure and gastrointestinal bleeding from angiodysplasia. RESULTS:: Angiodysplasia lesions were documented on traditional endoscopy and capsule endoscopy. Bleeding resolved after initiation of IV octreotide and did not recur on subcutaneous octreotide during the two year follow up period. CONCLUSIONS:: Based on the successful outcomes in the two patients, a trial of octreotide may be considered in pediatric patients who present with gastrointestinal bleeding secondary to angiodysplasia.

Original languageEnglish (US)
JournalJournal of Pediatric Gastroenterology and Nutrition
DOIs
StateAccepted/In press - Jun 13 2017

Fingerprint

Angiodysplasia
Octreotide
Heart Failure
Pediatrics
Hemorrhage
Capsule Endoscopy
Endoscopy
Heart Diseases

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

Cite this

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title = "Role of Octreotide in Pediatric Gastrointestinal Bleeding Secondary to Angiodysplasia in Children with Right Heart Failure",
abstract = "OBJECTIVES:: Angiodysplasia is a relatively uncommon cause of GI bleeding in children and may be seen in right heart failure. Octreotide has been used successfully in adult patients with gastrointestinal bleeding due to angiodysplasias. METHODS:: We describe two patients who had congenital heart disease with right heart failure and gastrointestinal bleeding from angiodysplasia. RESULTS:: Angiodysplasia lesions were documented on traditional endoscopy and capsule endoscopy. Bleeding resolved after initiation of IV octreotide and did not recur on subcutaneous octreotide during the two year follow up period. CONCLUSIONS:: Based on the successful outcomes in the two patients, a trial of octreotide may be considered in pediatric patients who present with gastrointestinal bleeding secondary to angiodysplasia.",
author = "Kanika Puri and Robert Caldwell and Jean Molleston",
year = "2017",
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doi = "10.1097/MPG.0000000000001659",
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T1 - Role of Octreotide in Pediatric Gastrointestinal Bleeding Secondary to Angiodysplasia in Children with Right Heart Failure

AU - Puri, Kanika

AU - Caldwell, Robert

AU - Molleston, Jean

PY - 2017/6/13

Y1 - 2017/6/13

N2 - OBJECTIVES:: Angiodysplasia is a relatively uncommon cause of GI bleeding in children and may be seen in right heart failure. Octreotide has been used successfully in adult patients with gastrointestinal bleeding due to angiodysplasias. METHODS:: We describe two patients who had congenital heart disease with right heart failure and gastrointestinal bleeding from angiodysplasia. RESULTS:: Angiodysplasia lesions were documented on traditional endoscopy and capsule endoscopy. Bleeding resolved after initiation of IV octreotide and did not recur on subcutaneous octreotide during the two year follow up period. CONCLUSIONS:: Based on the successful outcomes in the two patients, a trial of octreotide may be considered in pediatric patients who present with gastrointestinal bleeding secondary to angiodysplasia.

AB - OBJECTIVES:: Angiodysplasia is a relatively uncommon cause of GI bleeding in children and may be seen in right heart failure. Octreotide has been used successfully in adult patients with gastrointestinal bleeding due to angiodysplasias. METHODS:: We describe two patients who had congenital heart disease with right heart failure and gastrointestinal bleeding from angiodysplasia. RESULTS:: Angiodysplasia lesions were documented on traditional endoscopy and capsule endoscopy. Bleeding resolved after initiation of IV octreotide and did not recur on subcutaneous octreotide during the two year follow up period. CONCLUSIONS:: Based on the successful outcomes in the two patients, a trial of octreotide may be considered in pediatric patients who present with gastrointestinal bleeding secondary to angiodysplasia.

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