Role of the pathologist in active surveillance for prostate cancer

Roberta Mazzucchelli, Andrea B. Galosi, Matteo Santoni, Antonio Lopez-Beltran, Marina Scarpelli, Liang Cheng, Rodolfo Montironi

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Active surveillance (AS) is an alternative strategy that aims to minimize overtreatment by selecting only patients with significant prostate cancer (PCa) tumors for immediate treatment. Patients with favorable tumor characteristics are closely monitored using serum prostatespecific antigen (PSA) levels and serial biopsies of the prostate. In addition, other predictors of tumor progression, such as PSA doubling time, can be used during AS management. AS represents an excellent opportunity to identify molecular biomarkers of PCa behavior and to develop novel therapeutic strategies.

Original languageEnglish (US)
Pages (from-to)65-68
Number of pages4
JournalAnalytical and Quantitative Cytology and Histology
Volume37
Issue number1
StatePublished - Jan 1 2015

Keywords

  • Active surveillance
  • Immunohistochemistry
  • Prostate biopsy
  • Prostate cancer
  • Tumor extent

ASJC Scopus subject areas

  • Anatomy
  • Histology
  • Medicine(all)

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  • Cite this

    Mazzucchelli, R., Galosi, A. B., Santoni, M., Lopez-Beltran, A., Scarpelli, M., Cheng, L., & Montironi, R. (2015). Role of the pathologist in active surveillance for prostate cancer. Analytical and Quantitative Cytology and Histology, 37(1), 65-68.