Root resorptions associated with canine retraction treatment

Feifei Jiang, Jie Chen, Katherine Kula, Huiying Gu, Yansheng Du, George Eckert

Research output: Contribution to journalArticle

7 Scopus citations


Introduction The hypothesis of this study was that multiple factors are dominant in causing external apical root resorption (EARR). The objective of this investigation was to better understand the clinical factors that may lead to EARR. Methods Maxillary cone-beam computed tomography scans of 18 subjects who were treated with bilateral canine retractions during orthodontics were used to calculate EARR. The subjects were treated using well-calibrated segmental T-loops for delivering a 124-cN retraction force and the moment-to-force ratio suitable for moving the canine under either translation or controlled tipping. The subjects’ age, sex, treatment duration, and genotype were collected. Results Six subjects of the 18 showed definite EARR, meaning that load was not the only causing factor. All 5 subjects with the genotype identified had GG genotype of IL-1β rs11143634, indicating that people with this genotype may be at high risk. Longer treatment duration, female sex, and older age may also contribute to EARR, although the findings were not statistically significant. Conclusions EARR appears to be related to multiple factors. The orthodontic load and the genotype should be the focuses for future studies.

Original languageEnglish (US)
Pages (from-to)348-354
Number of pages7
JournalAmerican Journal of Orthodontics and Dentofacial Orthopedics
Issue number3
StatePublished - Sep 2017

ASJC Scopus subject areas

  • Orthodontics

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