Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p

Bolan Linghu, Judy Callis, Mark G. Goebl

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Abstract

In Saccharomyces cerevisiae, Rub1p, like ubiquitin, is conjugated to proteins. Before protein conjugation, the carboxyl-terminal asparagine residue of Rub1p is removed. Rub1p conjugation is dependent on the carboxyl-terminal processing enzyme Yuh1p, whereas Rub1p lacking the asparagine residue is conjugated without Yuh1p. Thus, Yuh1p is the major processing enzyme for Rub1p.

Original languageEnglish (US)
Pages (from-to)491-494
Number of pages4
JournalEukaryotic Cell
Volume1
Issue number3
DOIs
StatePublished - Jun 1 2002

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ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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