Screening colonoscopy in asymptomatic average-risk persons with negative fecal occult blood tests

Douglas Rex, Glen Lehman, Robert H. Hawes, Thomas Ulbright, Jennifer J. Smith

Research output: Contribution to journalArticle

214 Citations (Scopus)

Abstract

Colonoscopy was performed on 210 asymptomatic average-risk persons, aged 50-75 years, who had negative fecal occult blood test results. Colonoscopy was complete to the cecum in 209 subjects. Fifty-three subjects (25%) had adenomas and two had cancer. All of the adenomas ≥1 cm in size and both cancers occurred in subjects aged ≥60 years. Fifty-one percent of subjects with adenomas and one with cancer had no neoplasms distal to the sigmoid-descending colon junction. One subject had a major postpolypectomy hemorrhage that stopped spontaneously. Screening colonoscopy, therefore, has a high yield for detection of neoplasms in asymptomatic average-risk persons aged ≥60 years with negative fecal occult blood test results. The yield is low in persons aged 50-54 years and intermediate in persons aged 55-59 years.

Original languageEnglish
Pages (from-to)64-67
Number of pages4
JournalGastroenterology
Volume100
Issue number1
StatePublished - Jan 1991

Fingerprint

Occult Blood
Hematologic Tests
Colonoscopy
Adenoma
Neoplasms
Descending Colon
Cecum
Sigmoid Colon
Hemorrhage

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Screening colonoscopy in asymptomatic average-risk persons with negative fecal occult blood tests. / Rex, Douglas; Lehman, Glen; Hawes, Robert H.; Ulbright, Thomas; Smith, Jennifer J.

In: Gastroenterology, Vol. 100, No. 1, 01.1991, p. 64-67.

Research output: Contribution to journalArticle

@article{face7086241d4a829abaa01b6a2a972d,
title = "Screening colonoscopy in asymptomatic average-risk persons with negative fecal occult blood tests",
abstract = "Colonoscopy was performed on 210 asymptomatic average-risk persons, aged 50-75 years, who had negative fecal occult blood test results. Colonoscopy was complete to the cecum in 209 subjects. Fifty-three subjects (25{\%}) had adenomas and two had cancer. All of the adenomas ≥1 cm in size and both cancers occurred in subjects aged ≥60 years. Fifty-one percent of subjects with adenomas and one with cancer had no neoplasms distal to the sigmoid-descending colon junction. One subject had a major postpolypectomy hemorrhage that stopped spontaneously. Screening colonoscopy, therefore, has a high yield for detection of neoplasms in asymptomatic average-risk persons aged ≥60 years with negative fecal occult blood test results. The yield is low in persons aged 50-54 years and intermediate in persons aged 55-59 years.",
author = "Douglas Rex and Glen Lehman and Hawes, {Robert H.} and Thomas Ulbright and Smith, {Jennifer J.}",
year = "1991",
month = "1",
language = "English",
volume = "100",
pages = "64--67",
journal = "Gastroenterology",
issn = "0016-5085",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Screening colonoscopy in asymptomatic average-risk persons with negative fecal occult blood tests

AU - Rex, Douglas

AU - Lehman, Glen

AU - Hawes, Robert H.

AU - Ulbright, Thomas

AU - Smith, Jennifer J.

PY - 1991/1

Y1 - 1991/1

N2 - Colonoscopy was performed on 210 asymptomatic average-risk persons, aged 50-75 years, who had negative fecal occult blood test results. Colonoscopy was complete to the cecum in 209 subjects. Fifty-three subjects (25%) had adenomas and two had cancer. All of the adenomas ≥1 cm in size and both cancers occurred in subjects aged ≥60 years. Fifty-one percent of subjects with adenomas and one with cancer had no neoplasms distal to the sigmoid-descending colon junction. One subject had a major postpolypectomy hemorrhage that stopped spontaneously. Screening colonoscopy, therefore, has a high yield for detection of neoplasms in asymptomatic average-risk persons aged ≥60 years with negative fecal occult blood test results. The yield is low in persons aged 50-54 years and intermediate in persons aged 55-59 years.

AB - Colonoscopy was performed on 210 asymptomatic average-risk persons, aged 50-75 years, who had negative fecal occult blood test results. Colonoscopy was complete to the cecum in 209 subjects. Fifty-three subjects (25%) had adenomas and two had cancer. All of the adenomas ≥1 cm in size and both cancers occurred in subjects aged ≥60 years. Fifty-one percent of subjects with adenomas and one with cancer had no neoplasms distal to the sigmoid-descending colon junction. One subject had a major postpolypectomy hemorrhage that stopped spontaneously. Screening colonoscopy, therefore, has a high yield for detection of neoplasms in asymptomatic average-risk persons aged ≥60 years with negative fecal occult blood test results. The yield is low in persons aged 50-54 years and intermediate in persons aged 55-59 years.

UR - http://www.scopus.com/inward/record.url?scp=0025961550&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025961550&partnerID=8YFLogxK

M3 - Article

VL - 100

SP - 64

EP - 67

JO - Gastroenterology

JF - Gastroenterology

SN - 0016-5085

IS - 1

ER -