Secondary ovarian neoplasia. A clinicopathologic study of 35 cases

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Abstract

The authors reviewed the clinical and pathologic features of 35 cases of secondary ovarian neoplasms in which the clinical presentation was that of a primary ovarian tumor. The most common secondary neoplasms to mimic an ovarian tumor were colonic adenocarcinoma, breast carcinoma, lymphoma, carcinoid, and gastric adenocarcinoma. It was found that a classification based on gross appearance was useful in evaluating these neoplasms. Solid neoplasms with either a diffuse or nodular gross appareance had distinct histologies so that accurate diagnosis was possible. Cystic neoplasms, especially colon adenocarcinomas, were deceptive and frequently misclassified as primary ovarian adenocarcinoma. Since all of the metastatic colonic carcinomas had mucus-containing cells, the main differential diagnosis was between metastatic colonic carcinoma and primary mucinous carcinoma of the ovary. The absence of a mucus-cell predominant pattern and the lack of transition from benign-appearing epithelium to malignant epithelium are two useful criteria in making this important distinction. Other features may also prove helpful.

Original languageEnglish
Pages (from-to)1164-1174
Number of pages11
JournalCancer
Volume53
Issue number5
StatePublished - 1984

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Adenocarcinoma
Mucus
Neoplasms
Epithelium
Carcinoma
Mucinous Adenocarcinoma
Carcinoid Tumor
Ovarian Neoplasms
Colonic Neoplasms
Ovary
Histology
Differential Diagnosis
Breast Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Secondary ovarian neoplasia. A clinicopathologic study of 35 cases. / Ulbright, Thomas; Roth, L. M.; Stehman, Frederick.

In: Cancer, Vol. 53, No. 5, 1984, p. 1164-1174.

Research output: Contribution to journalArticle

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