Secretory proteins in the perfused human placenta

Joseph Dancis, N. K. Ghosh, V. Jansen, H. Schneider, R. J. Fallon, R. P. Cox

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A relatively simple perfusion technique of human placenta has been applied to the study of secretory proteins. Preferential secretion into the maternal circulation of human chorionic gonadotropin (HCG), human chorionic somatomammotropin (HCS), follicle-stimulating hormone (FSH), and placental alkaline phosphatase has been demonstrated, contrasting with the bidirectional secretion of progesterone. Evidence is presented for the net synthesis of HCS during perfusion. The technique offers advantages in the study of synthesis and secretion of placental materials.

Original languageEnglish (US)
Pages (from-to)188-193
Number of pages6
JournalNeonatology
Volume35
Issue number3-4
DOIs
StatePublished - Jan 1 1979

Keywords

  • Hormones
  • Human placenta
  • Perfusion
  • Proteins
  • Secretion

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Biology

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