Self-administration of subcutaneous depot medroxyprogesterone acetate by adolescent women

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19 Citations (Scopus)

Abstract

Background Intramuscular depot medroxyprogesterone acetate (DMPA-IM) is now available in subcutaneous (SC) formulation, potentially allowing for home-based self-administration. We examined adolescents' interest in and proficiency at DMPA-SC self-administration. Study Design This is a planned secondary analysis of a randomized controlled trial comparing pain between DMPA-IM and DMPA-SC. In the trial, study participants (N= 55) aged 14-21 years were recruited at DMPA initiation and randomized to receive DMPA-IM or DMPA-SC. Participants received the alternate formulation at 3 months, chose formulation at 6 months and could learn self-administration at 9 months. The current analysis is of the women who chose self-administration of DMPA-SC. Proficiency was rated for each step of self-administration: independently [I], with reassurance [R], with verbal instruction [V] or nurse performed [RN]. Data were analyzed using descriptive and comparative statistics. Results Thirty-five percent (19/55) of participants learned self-administration. Proficiency ratings were as follows: chose injection site (I=78.9%, R=5.3%, V=5.3%, RN=10.5%), cleaned site (I=89.5%, RN=10.5%), assembled injection device (I=47.4%, R=36.8%, V=15.8%), self-injected (I=31.6%, R=36.8%, V=15.8%, RN=15.8%) and disposed of device (I=21.1%, R=21.1%, RN=57.9%). Conclusions Many adolescents are interested in and capable of DMPA-SC self-administration with brief education and minimal assistance.

Original languageEnglish
Pages (from-to)401-407
Number of pages7
JournalContraception
Volume88
Issue number3
DOIs
StatePublished - Sep 2013

Fingerprint

Medroxyprogesterone Acetate
Self Administration
N,N-dimethyl-4-anisidine
Equipment and Supplies
Injections
Randomized Controlled Trials
Nurses
Education
Pain

Keywords

  • Adolescent
  • Contraception
  • Depot medroxyprogesterone acetate
  • Self-injection

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

@article{673a89d067244810bdfdd932adbdddce,
title = "Self-administration of subcutaneous depot medroxyprogesterone acetate by adolescent women",
abstract = "Background Intramuscular depot medroxyprogesterone acetate (DMPA-IM) is now available in subcutaneous (SC) formulation, potentially allowing for home-based self-administration. We examined adolescents' interest in and proficiency at DMPA-SC self-administration. Study Design This is a planned secondary analysis of a randomized controlled trial comparing pain between DMPA-IM and DMPA-SC. In the trial, study participants (N= 55) aged 14-21 years were recruited at DMPA initiation and randomized to receive DMPA-IM or DMPA-SC. Participants received the alternate formulation at 3 months, chose formulation at 6 months and could learn self-administration at 9 months. The current analysis is of the women who chose self-administration of DMPA-SC. Proficiency was rated for each step of self-administration: independently [I], with reassurance [R], with verbal instruction [V] or nurse performed [RN]. Data were analyzed using descriptive and comparative statistics. Results Thirty-five percent (19/55) of participants learned self-administration. Proficiency ratings were as follows: chose injection site (I=78.9{\%}, R=5.3{\%}, V=5.3{\%}, RN=10.5{\%}), cleaned site (I=89.5{\%}, RN=10.5{\%}), assembled injection device (I=47.4{\%}, R=36.8{\%}, V=15.8{\%}), self-injected (I=31.6{\%}, R=36.8{\%}, V=15.8{\%}, RN=15.8{\%}) and disposed of device (I=21.1{\%}, R=21.1{\%}, RN=57.9{\%}). Conclusions Many adolescents are interested in and capable of DMPA-SC self-administration with brief education and minimal assistance.",
keywords = "Adolescent, Contraception, Depot medroxyprogesterone acetate, Self-injection",
author = "Rebekah Williams and Devon Hensel and J. Fortenberry",
year = "2013",
month = "9",
doi = "10.1016/j.contraception.2012.11.019",
language = "English",
volume = "88",
pages = "401--407",
journal = "Contraception",
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T1 - Self-administration of subcutaneous depot medroxyprogesterone acetate by adolescent women

AU - Williams, Rebekah

AU - Hensel, Devon

AU - Fortenberry, J.

PY - 2013/9

Y1 - 2013/9

N2 - Background Intramuscular depot medroxyprogesterone acetate (DMPA-IM) is now available in subcutaneous (SC) formulation, potentially allowing for home-based self-administration. We examined adolescents' interest in and proficiency at DMPA-SC self-administration. Study Design This is a planned secondary analysis of a randomized controlled trial comparing pain between DMPA-IM and DMPA-SC. In the trial, study participants (N= 55) aged 14-21 years were recruited at DMPA initiation and randomized to receive DMPA-IM or DMPA-SC. Participants received the alternate formulation at 3 months, chose formulation at 6 months and could learn self-administration at 9 months. The current analysis is of the women who chose self-administration of DMPA-SC. Proficiency was rated for each step of self-administration: independently [I], with reassurance [R], with verbal instruction [V] or nurse performed [RN]. Data were analyzed using descriptive and comparative statistics. Results Thirty-five percent (19/55) of participants learned self-administration. Proficiency ratings were as follows: chose injection site (I=78.9%, R=5.3%, V=5.3%, RN=10.5%), cleaned site (I=89.5%, RN=10.5%), assembled injection device (I=47.4%, R=36.8%, V=15.8%), self-injected (I=31.6%, R=36.8%, V=15.8%, RN=15.8%) and disposed of device (I=21.1%, R=21.1%, RN=57.9%). Conclusions Many adolescents are interested in and capable of DMPA-SC self-administration with brief education and minimal assistance.

AB - Background Intramuscular depot medroxyprogesterone acetate (DMPA-IM) is now available in subcutaneous (SC) formulation, potentially allowing for home-based self-administration. We examined adolescents' interest in and proficiency at DMPA-SC self-administration. Study Design This is a planned secondary analysis of a randomized controlled trial comparing pain between DMPA-IM and DMPA-SC. In the trial, study participants (N= 55) aged 14-21 years were recruited at DMPA initiation and randomized to receive DMPA-IM or DMPA-SC. Participants received the alternate formulation at 3 months, chose formulation at 6 months and could learn self-administration at 9 months. The current analysis is of the women who chose self-administration of DMPA-SC. Proficiency was rated for each step of self-administration: independently [I], with reassurance [R], with verbal instruction [V] or nurse performed [RN]. Data were analyzed using descriptive and comparative statistics. Results Thirty-five percent (19/55) of participants learned self-administration. Proficiency ratings were as follows: chose injection site (I=78.9%, R=5.3%, V=5.3%, RN=10.5%), cleaned site (I=89.5%, RN=10.5%), assembled injection device (I=47.4%, R=36.8%, V=15.8%), self-injected (I=31.6%, R=36.8%, V=15.8%, RN=15.8%) and disposed of device (I=21.1%, R=21.1%, RN=57.9%). Conclusions Many adolescents are interested in and capable of DMPA-SC self-administration with brief education and minimal assistance.

KW - Adolescent

KW - Contraception

KW - Depot medroxyprogesterone acetate

KW - Self-injection

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DO - 10.1016/j.contraception.2012.11.019

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JO - Contraception

JF - Contraception

SN - 0010-7824

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