Separation of double-label liquid scintillation samples by half-life

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2 Citations (Scopus)

Abstract

A method is presented for separation of double- or triple-labeled liquid scintillation samples based on the partial decay of one of the nuclides. Validity of the procedure has been demonstrated with the following combinations of nuclides commonly encountered in laboratory situations; 131I-14C, 32P-14C, and 203Hg-14C, Separation of all nuclide pairs agrees favorably with predieted values except when the activity ratios exceed 103. The determinations are independent of quenching and nuclide spectra and greatly augment the number of β-β and β-γ combinations resolved by liquid scintillation spectrometry. The utility of this method for separation of triple-labeled samples is discussed.

Original languageEnglish
Pages (from-to)109-118
Number of pages10
JournalAnalytical Biochemistry
Volume83
Issue number1
DOIs
StatePublished - 1977

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Scintillation
Isotopes
Half-Life
Labels
Liquids
Spectrum Analysis
Spectrometry
Quenching

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Separation of double-label liquid scintillation samples by half-life. / Olson, Kenneth.

In: Analytical Biochemistry, Vol. 83, No. 1, 1977, p. 109-118.

Research output: Contribution to journalArticle

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