Sequences at the 3′ ends of yeast viral dsRNAs: Proposed transcriptase and replicase initiation sites

Victoria E. Brennan, Loren Field, Paul Cizdziel, Jeremy A. Bruenn

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

ScV is a double-stranded RNA virus of yeast consisting of two separately encapsidated dsRNAs (L and M). ScV-1 and ScV-2 are two dsRNA viruses present in two different yeast killer strains, K1 and K2. Our 3′ end sequence analysis shows that the two sets of viral dsRNAs from ScV-1 and ScV-2 are very similar. Consensus sequences for transcriptase and replicase initiation are proposed. A stem and loop structure with a 3′ terminal AUGC sequence, like that of several plant virus plus strand RNAs, is present at the putative replicase initiation site of one of the yeast viral RNA plus strands.

Original languageEnglish (US)
Pages (from-to)4007-4021
Number of pages15
JournalNucleic acids research
Volume9
Issue number16
DOIs
StatePublished - Aug 25 1981
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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