Serum tumor markers in testicular cancer

Yaron Ehrlich, Stephen D.W. Beck, Richard S. Foster, Richard Bihrle, Lawrence H. Einhorn

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

Testicular cancer has become a model for a curable neoplasm, where biochemical markers play a critical role. Serum tumor markers are integral in patient management and contributes to the diagnosis, staging, and risk assessment, as well as evaluation of response to therapy and detection of relapse. We review their biochemistry, biology, and clinical use in the setting of localized and metastatic disease. The integration of tumor markers in prognostic models as well as the significance of marker kinetics during chemotherapy is discussed.

Original languageEnglish (US)
Pages (from-to)17-23
Number of pages7
JournalUrologic Oncology: Seminars and Original Investigations
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2013

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Keywords

  • Chemotherapy
  • Prognosis
  • Serum tumor markers
  • Testicular neoplasia

ASJC Scopus subject areas

  • Oncology
  • Urology

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