Sex differences in semantic language processing: A functional MRI study

L. C. Baxter, Andrew Saykin, L. A. Flashman, S. C. Johnson, S. J. Guerin, D. R. Babcock, H. A. Wishart

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

Predictions based on two models of sex differences in cerebral organization of language were compared by examining fMRI patterns of 10 females and 9 males during a semantic processing task. Both groups displayed activation of left inferior frontal gyrus (IFG), left superior temporal gyrus (STG), and cingulate. Females, but not males, showed bilateral IFG and STG activation. Further analyses revealed females had less diffuse left activation and greater right posterior temporal and insula region activation than males. Results support both an interhemispheric and an intrahemispheric model of sex differences in language, suggesting that the models may not be mutually exclusive.

Original languageEnglish (US)
Pages (from-to)264-272
Number of pages9
JournalBrain and Language
Volume84
Issue number2
DOIs
StatePublished - Feb 2003
Externally publishedYes

Fingerprint

Temporal Lobe
Semantics
Sex Characteristics
activation
Language
semantics
Magnetic Resonance Imaging
Prefrontal Cortex
language
organization
Language Processing
Sex Differences
Functional MRI
Activation
Group

Keywords

  • Functional MRI
  • Language
  • Lateralization
  • Semantic memory
  • Sex differences

ASJC Scopus subject areas

  • Language and Linguistics
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)

Cite this

Baxter, L. C., Saykin, A., Flashman, L. A., Johnson, S. C., Guerin, S. J., Babcock, D. R., & Wishart, H. A. (2003). Sex differences in semantic language processing: A functional MRI study. Brain and Language, 84(2), 264-272. https://doi.org/10.1016/S0093-934X(02)00549-7

Sex differences in semantic language processing : A functional MRI study. / Baxter, L. C.; Saykin, Andrew; Flashman, L. A.; Johnson, S. C.; Guerin, S. J.; Babcock, D. R.; Wishart, H. A.

In: Brain and Language, Vol. 84, No. 2, 02.2003, p. 264-272.

Research output: Contribution to journalArticle

Baxter, LC, Saykin, A, Flashman, LA, Johnson, SC, Guerin, SJ, Babcock, DR & Wishart, HA 2003, 'Sex differences in semantic language processing: A functional MRI study', Brain and Language, vol. 84, no. 2, pp. 264-272. https://doi.org/10.1016/S0093-934X(02)00549-7
Baxter, L. C. ; Saykin, Andrew ; Flashman, L. A. ; Johnson, S. C. ; Guerin, S. J. ; Babcock, D. R. ; Wishart, H. A. / Sex differences in semantic language processing : A functional MRI study. In: Brain and Language. 2003 ; Vol. 84, No. 2. pp. 264-272.
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