Sexual behaviour, STDs and risks for prostate cancer

R. B. Hayes, L. M. Pottern, H. Strickler, C. Rabkin, V. Pope, G. M. Swanson, R. S. Greenberg, J. B. Schoenberg, J. Liff, A. G. Schwartz, R. N. Hoover, J. F. Fraumeni

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

A population-based case-control study was carried out among 981 men (479 black, 502 white) with pathologically confirmed prostate cancer and 1315 controls (594 black, 721 white). In-person interviews elicited information on sexual behaviour and other potential risk factors for prostate cancer. Blood was drawn for serologic studies in a subset of the cases (n = 276) and controls (n = 295). Prostate cancer risk was increased among men who reported a history of gonorrhoea or syphilis (odds ratio (OR) = 1.6; 95% confidence internal (CI) 1.2-2.1) or showed serological evidence of syphilis (MHA-TP) (OR = 1.8, 95% CI 1.0-3.5). Patterns of risk for gonorrhoea and syphilis were similar for blacks (OR = 1.7; 95% CI 1.2-2.2) and whites (OR = 1.6, 95% CI 0.8-3.2). Risks increased with increasing occurrences of gonorrhoea, rising to OR = 3.3 (95% CI 1.4-7.8) among subjects with three or more events (P(trend) = 0.0005). Frequent sexual encounters with prostitutes and failure to use condoms were also associated with increased risk. Syphilis, gonorrhoea, sex with prostitutes and unprotected sexual intercourse may be indicators of contact with a sexually transmissible factor that increases the risk of prostate cancer. (C) 2000 Cancer Research Campaign.

Original languageEnglish (US)
Pages (from-to)718-725
Number of pages8
JournalBritish Journal of Cancer
Volume82
Issue number3
StatePublished - 2000
Externally publishedYes

Fingerprint

Sexually Transmitted Diseases
Sexual Behavior
Gonorrhea
Syphilis
Prostatic Neoplasms
Odds Ratio
Sex Workers
Coitus
Condoms
Case-Control Studies
Interviews
Population
hydroquinone

Keywords

  • Epidemiology
  • Prostatic neoplasms
  • Racial aspects
  • Sexual behaviour

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Hayes, R. B., Pottern, L. M., Strickler, H., Rabkin, C., Pope, V., Swanson, G. M., ... Fraumeni, J. F. (2000). Sexual behaviour, STDs and risks for prostate cancer. British Journal of Cancer, 82(3), 718-725.

Sexual behaviour, STDs and risks for prostate cancer. / Hayes, R. B.; Pottern, L. M.; Strickler, H.; Rabkin, C.; Pope, V.; Swanson, G. M.; Greenberg, R. S.; Schoenberg, J. B.; Liff, J.; Schwartz, A. G.; Hoover, R. N.; Fraumeni, J. F.

In: British Journal of Cancer, Vol. 82, No. 3, 2000, p. 718-725.

Research output: Contribution to journalArticle

Hayes, RB, Pottern, LM, Strickler, H, Rabkin, C, Pope, V, Swanson, GM, Greenberg, RS, Schoenberg, JB, Liff, J, Schwartz, AG, Hoover, RN & Fraumeni, JF 2000, 'Sexual behaviour, STDs and risks for prostate cancer', British Journal of Cancer, vol. 82, no. 3, pp. 718-725.
Hayes RB, Pottern LM, Strickler H, Rabkin C, Pope V, Swanson GM et al. Sexual behaviour, STDs and risks for prostate cancer. British Journal of Cancer. 2000;82(3):718-725.
Hayes, R. B. ; Pottern, L. M. ; Strickler, H. ; Rabkin, C. ; Pope, V. ; Swanson, G. M. ; Greenberg, R. S. ; Schoenberg, J. B. ; Liff, J. ; Schwartz, A. G. ; Hoover, R. N. ; Fraumeni, J. F. / Sexual behaviour, STDs and risks for prostate cancer. In: British Journal of Cancer. 2000 ; Vol. 82, No. 3. pp. 718-725.
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