Short bowel syndrome in infancy and childhood. Analysis of survival in 60 patients

Jay L. Grosfeld, Frederick J. Rescoria, Karen W. West

Research output: Contribution to journalArticle

107 Scopus citations

Abstract

This report concerns 60 infants and children with short bowel syndrome, most commonly caused by necrotizing enterocolitis in this study. Resection of atretic or gangrenous bowel was performed in 53 patients, tapering enteroplasty and primary anastomosis was performed in 13 patients, and temporary enterostomies were performed in 40 patients. Second-look laparotomy was useful in two of four cases of questionable bowel viability. The ileocecal valve was resected in 33 patients and remained intact in 27. The mean length of remaining bowel was 58.4 cm (range 13 to 150 cm). Seven patients with total aganglionosis and mid to proximal small bowel extension were managed with an initial enterostomy, whereas three had a pull-through procedure with an aganglionic patch enteroplasty. All patients received total parenteral nutrition and early enteral feedings. Home hyperalimentation was attempted when 50 percent of the calorie intake was enteral. Intestinal adaptation required from 3 to 14 months. Frequent setbacks were related to catheter sepsis, rotavirus infection, carbohydrate intolerance, and liver dysfunction. The overall survival rate was 85 percent, with mortality due to liver failure and sepsis associated with total parenteral nutrition.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalThe American Journal of Surgery
Volume151
Issue number1
DOIs
StatePublished - Jan 1986
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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