Signal transduction via unstructured protein conduits

A. Keith Dunker, Vladimir N. Uversky

Research output: Contribution to journalShort survey

120 Scopus citations


Signaling via phosphorylation-regulated protein-protein interactions often involves flexible or unstructured proteins. Detailed biophysical and computational studies on one such interaction reveal a marvelously intricate, temporally regulated, multistep conduit for signal transduction in the cell cycle.

Original languageEnglish (US)
Pages (from-to)229-230
Number of pages2
JournalNature Chemical Biology
Issue number4
StatePublished - Apr 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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