Single-column gas chromatographic separation of nanomolar quantities of amino acids

William J. McBride, Jack D. Klingman

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Three gas chromatography packings are reported that can be used to separate mixtures of amino acids present in nanomolar quantities. These packings can be used with single column operation without bleed interference. The best separation was achieved with 1.2% PDEAS on Gas Chrom A which had been carefully prepared and conditioned. Preliminary data are presented which indicate that gas chromatography can be used to analyze amino acids present in nanomolar quantities in biological samples.

Original languageEnglish (US)
Pages (from-to)109-122
Number of pages14
JournalAnalytical biochemistry
Volume25
Issue numberC
DOIs
StatePublished - 1968

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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