Single photon emission computed tomography (SPECT) brain imaging: Usingn, N, N, N′-trimethyl-N′-(2 hydro-y-3-methyl-5-<sup>123</sup>i-iodobenzyl)-1,3-propanediamine 2 HC1 (HIPDM):Intractable complex partial seizures

B. I. Lee, Omkar Markand, A. R. Siddiqui, H. M. Park, B. Mock, H. H. Wellman, R. M. Worth, M. K. Edwards

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

HIPDM-SPECT brain imaging was performed in four patients with intractable complex partial seizures (CPS). Three patients had an epileptogenic focus in one temporal lobe and underwent anterior temporal lobectomy. Interictal HIPDM-SPECT demonstrated decreased regional cerebral perfusion (rCP) in the epileptogenic area in only one patient, but ictal studies showed increased rCP in the epileptic foci of all three patients. In the fourth patient, interictal HIPDM-SPECT showed increased rCP in the area of epileptogenic focus; when antiepileptic medication was taken, rCP decreased, HIPDM-SPECT brain imaging is useful for localizing epileptogenic foci in CPS.

Original languageEnglish
Pages (from-to)1471-1477
Number of pages7
JournalNeurology
Volume36
Issue number11
StatePublished - 1986

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Single-Photon Emission-Computed Tomography
Neuroimaging
Seizures
Perfusion
Anterior Temporal Lobectomy
Temporal Lobe
Anticonvulsants
Stroke
trimethylenediamine
N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine
Computed Tomography
Brain Imaging

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Single photon emission computed tomography (SPECT) brain imaging : Usingn, N, N, N′-trimethyl-N′-(2 hydro-y-3-methyl-5-<sup>123</sup>i-iodobenzyl)-1,3-propanediamine 2 HC1 (HIPDM):Intractable complex partial seizures. / Lee, B. I.; Markand, Omkar; Siddiqui, A. R.; Park, H. M.; Mock, B.; Wellman, H. H.; Worth, R. M.; Edwards, M. K.

In: Neurology, Vol. 36, No. 11, 1986, p. 1471-1477.

Research output: Contribution to journalArticle

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