Skeletal Imaging

Matthew R. Allen, Kelly Krohn

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

One fundamental way to assess skeletal health is through imaging. In the clinic, skeletal imaging is used to confirm and classify fractures, diagnose osteoporosis, assess intervention efficacy, and identify regions of high metabolic activity. In the laboratory, imaging is commonly used as a first approach to determine skeletal phenotypes associated with genetic modifications of animals and also to assess experimental manipulations. Several options exist for skeletal imaging, including conventional radiography (plain X-ray), dual energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and radionuclide imaging. Ultrasound also can be used noninvasively to assess bone density and elastic modulus. Each of these imaging tools has both strengths and weaknesses. The choice of method ultimately depends on which provides the necessary information with the least consequences (most often radiation exposure) to the subject.

Original languageEnglish (US)
Title of host publicationBasic and Applied Bone Biology
PublisherElsevier Inc.
Pages93-113
Number of pages21
ISBN (Print)9780124160156
DOIs
StatePublished - Aug 12 2013

Keywords

  • Computed tomography
  • Dual-energy X-ray absorptiometry
  • Finite element analysis
  • Micro-CT
  • Radiography
  • Skeletal imaging

ASJC Scopus subject areas

  • Medicine(all)
  • Dentistry(all)

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  • Cite this

    Allen, M. R., & Krohn, K. (2013). Skeletal Imaging. In Basic and Applied Bone Biology (pp. 93-113). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-416015-6.00005-8