Skeletal Imaging

Matthew Allen, Kelly Krohn

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

One fundamental way to assess skeletal health is through imaging. In the clinic, skeletal imaging is used to confirm and classify fractures, diagnose osteoporosis, assess intervention efficacy, and identify regions of high metabolic activity. In the laboratory, imaging is commonly used as a first approach to determine skeletal phenotypes associated with genetic modifications of animals and also to assess experimental manipulations. Several options exist for skeletal imaging, including conventional radiography (plain X-ray), dual energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and radionuclide imaging. Ultrasound also can be used noninvasively to assess bone density and elastic modulus. Each of these imaging tools has both strengths and weaknesses. The choice of method ultimately depends on which provides the necessary information with the least consequences (most often radiation exposure) to the subject.

Original languageEnglish
Title of host publicationBasic and Applied Bone Biology
PublisherElsevier Inc.
Pages93-113
Number of pages21
ISBN (Print)9780124160156
DOIs
StatePublished - Aug 12 2013

Fingerprint

X Ray Computed Tomography
Elastic Modulus
Photon Absorptiometry
Radiography
Radionuclide Imaging
Bone Density
Osteoporosis
Magnetic Resonance Imaging
X-Rays
Phenotype
Health
Radiation Exposure

Keywords

  • Computed tomography
  • Dual-energy X-ray absorptiometry
  • Finite element analysis
  • Micro-CT
  • Radiography
  • Skeletal imaging

ASJC Scopus subject areas

  • Medicine(all)
  • Dentistry(all)

Cite this

Allen, M., & Krohn, K. (2013). Skeletal Imaging. In Basic and Applied Bone Biology (pp. 93-113). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-416015-6.00005-8

Skeletal Imaging. / Allen, Matthew; Krohn, Kelly.

Basic and Applied Bone Biology. Elsevier Inc., 2013. p. 93-113.

Research output: Chapter in Book/Report/Conference proceedingChapter

Allen, M & Krohn, K 2013, Skeletal Imaging. in Basic and Applied Bone Biology. Elsevier Inc., pp. 93-113. https://doi.org/10.1016/B978-0-12-416015-6.00005-8
Allen M, Krohn K. Skeletal Imaging. In Basic and Applied Bone Biology. Elsevier Inc. 2013. p. 93-113 https://doi.org/10.1016/B978-0-12-416015-6.00005-8
Allen, Matthew ; Krohn, Kelly. / Skeletal Imaging. Basic and Applied Bone Biology. Elsevier Inc., 2013. pp. 93-113
@inbook{9918e164b3dc427cbdb138986fa4e1f1,
title = "Skeletal Imaging",
abstract = "One fundamental way to assess skeletal health is through imaging. In the clinic, skeletal imaging is used to confirm and classify fractures, diagnose osteoporosis, assess intervention efficacy, and identify regions of high metabolic activity. In the laboratory, imaging is commonly used as a first approach to determine skeletal phenotypes associated with genetic modifications of animals and also to assess experimental manipulations. Several options exist for skeletal imaging, including conventional radiography (plain X-ray), dual energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and radionuclide imaging. Ultrasound also can be used noninvasively to assess bone density and elastic modulus. Each of these imaging tools has both strengths and weaknesses. The choice of method ultimately depends on which provides the necessary information with the least consequences (most often radiation exposure) to the subject.",
keywords = "Computed tomography, Dual-energy X-ray absorptiometry, Finite element analysis, Micro-CT, Radiography, Skeletal imaging",
author = "Matthew Allen and Kelly Krohn",
year = "2013",
month = "8",
day = "12",
doi = "10.1016/B978-0-12-416015-6.00005-8",
language = "English",
isbn = "9780124160156",
pages = "93--113",
booktitle = "Basic and Applied Bone Biology",
publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Skeletal Imaging

AU - Allen, Matthew

AU - Krohn, Kelly

PY - 2013/8/12

Y1 - 2013/8/12

N2 - One fundamental way to assess skeletal health is through imaging. In the clinic, skeletal imaging is used to confirm and classify fractures, diagnose osteoporosis, assess intervention efficacy, and identify regions of high metabolic activity. In the laboratory, imaging is commonly used as a first approach to determine skeletal phenotypes associated with genetic modifications of animals and also to assess experimental manipulations. Several options exist for skeletal imaging, including conventional radiography (plain X-ray), dual energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and radionuclide imaging. Ultrasound also can be used noninvasively to assess bone density and elastic modulus. Each of these imaging tools has both strengths and weaknesses. The choice of method ultimately depends on which provides the necessary information with the least consequences (most often radiation exposure) to the subject.

AB - One fundamental way to assess skeletal health is through imaging. In the clinic, skeletal imaging is used to confirm and classify fractures, diagnose osteoporosis, assess intervention efficacy, and identify regions of high metabolic activity. In the laboratory, imaging is commonly used as a first approach to determine skeletal phenotypes associated with genetic modifications of animals and also to assess experimental manipulations. Several options exist for skeletal imaging, including conventional radiography (plain X-ray), dual energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and radionuclide imaging. Ultrasound also can be used noninvasively to assess bone density and elastic modulus. Each of these imaging tools has both strengths and weaknesses. The choice of method ultimately depends on which provides the necessary information with the least consequences (most often radiation exposure) to the subject.

KW - Computed tomography

KW - Dual-energy X-ray absorptiometry

KW - Finite element analysis

KW - Micro-CT

KW - Radiography

KW - Skeletal imaging

UR - http://www.scopus.com/inward/record.url?scp=84902052525&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902052525&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-416015-6.00005-8

DO - 10.1016/B978-0-12-416015-6.00005-8

M3 - Chapter

AN - SCOPUS:84902052525

SN - 9780124160156

SP - 93

EP - 113

BT - Basic and Applied Bone Biology

PB - Elsevier Inc.

ER -