Sleep-disordered breathing in obese adolescents is associated with visceral adiposity and markers of insulin resistance

Tamara S. Hannon, Sojung Lee, Sangeeta Chakravorty, Yan Lin, Silva A. Arslanian

Research output: Contribution to journalShort surveypeer-review

40 Scopus citations


Sleep-disordered breathing is associated with obesity, insulin resistance, and the metabolic syndrome in adults. Similar data in children is limited and conflicting. This pilot study examined the relationships between sleep-disordered breathing, visceral adiposity, and cardiometabolic risk factors in obese adolescents. Twenty obese (body mass index ≥95th percentile), otherwise healthy adolescents (age 14.9 ± 2 years) underwent polysomnogram studies, fasting lipid profile and oral glucose tolerance tests, and measures of body composition (dual-energy X-ray absorptiometry) and visceral adiposity (abdominal computed tomography). The severity of sleep-disordered breathing (as measured by apnea-hypopnea index) was positively associated with visceral adipose tissue (r=0.73, p<0.001) but not with other measures of body composition. After controlling for body mass index, the severity of sleep-disordered breathing was positively associated with markers of insulin resistance (homeostasis model assessment and fasting insulin). Further study to allow for critical assessment of the relationships between sleep-disordered breathing and cardiometabolic risk factors in obese youth remains necessary.

Original languageEnglish (US)
Pages (from-to)157-160
Number of pages4
JournalInternational Journal of Pediatric Obesity
Issue number2
StatePublished - Apr 2011


  • Sleep apnea
  • abdominal obesity
  • central adiposity
  • insulin resistance

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Health Policy
  • Nutrition and Dietetics
  • Public Health, Environmental and Occupational Health

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