Smoking and the risk of type 2 diabetes

Judith Maddatu, Emily Anderson-Baucum, Carmella Evans-Molina

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Despite accumulating evidence demonstrating strong epidemiologic and mechanistic associations between cigarette smoking, hyperglycemia, and the development of type 2 diabetes, tobacco abuse has not been uniformly recognized as a modifiable risk factor in diabetes prevention or screening strategies. In this review, we highlight population-based studies that have linked cigarette smoking with an increased risk of type 2 diabetes and summarize clinical and preclinical studies offering insight into mechanisms through which cigarette smoking and nicotine exposure impact body composition, insulin sensitivity, and pancreatic β cell function. Key questions for future studies are identified and strategies for smoking cessation as a means to decrease diabetes risk are discussed.

Original languageEnglish (US)
JournalTranslational Research
DOIs
StateAccepted/In press - Dec 6 2016

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Medical problems
Type 2 Diabetes Mellitus
Smoking
Tobacco Products
Smoking Cessation
Body Composition
Nicotine
Hyperglycemia
Tobacco
Insulin Resistance
Screening
Insulin
Population
Chemical analysis

ASJC Scopus subject areas

  • Medicine(all)
  • Public Health, Environmental and Occupational Health
  • Biochemistry, medical

Cite this

Smoking and the risk of type 2 diabetes. / Maddatu, Judith; Anderson-Baucum, Emily; Evans-Molina, Carmella.

In: Translational Research, 06.12.2016.

Research output: Contribution to journalArticle

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