Internal architecture of scaffolds, including pore size, pore shape, and connectivity, are critical to the in vivo and mechanical performance of the scaffolds. It affects the degree of bone regeneration,1-5 influences the path of bone regeneration,6 and determines the mechanical properties of the scaffolds. However, in many scaffold manufacturing techniques, the control over the internal architecture and interconnectivity is limited. Current scaffold processing techniques, including solvent casting, freeze-drying, phase separation, and gas forming, can now produce interconnected microporosity with a certain degree of oriented pore structure.
|Original language||English (US)|
|Title of host publication||Scaffolding in Tissue Engineering|
|Number of pages||16|
|State||Published - Jan 1 2005|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Materials Science(all)