Solid-phase synthesis of tetrasubstituted pyrrolo[2,3-d]pyrimidines

Ji Hoon Lee, Hyun Suk Lim

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

A facile solid phase synthesis of 2,4,6,7-tetrasubstituted pyrrolo[2,3-d]pyrimidines is described. The synthesis involves a highly efficient five-step route starting from resin-bound dimeric peptoids. To demonstrate the versatility of our method, a representative library of 108 tetrasubstituted pyrrolo[2,3-d]pyrimidines of high quality was synthesized. This journal is

Original languageEnglish (US)
Pages (from-to)4229-4235
Number of pages7
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number21
DOIs
StatePublished - Jun 7 2012

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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