Solid-phase synthesis of tetrasubstituted pyrrolo[2,3-d]pyrimidines

Ji Hoon Lee, Hyun-Suk Lim

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A facile solid phase synthesis of 2,4,6,7-tetrasubstituted pyrrolo[2,3-d]pyrimidines is described. The synthesis involves a highly efficient five-step route starting from resin-bound dimeric peptoids. To demonstrate the versatility of our method, a representative library of 108 tetrasubstituted pyrrolo[2,3-d]pyrimidines of high quality was synthesized. This journal is

Original languageEnglish
Pages (from-to)4229-4235
Number of pages7
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number21
DOIs
StatePublished - Jun 7 2012

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Solid-Phase Synthesis Techniques
pyrimidines
solid phases
Peptoids
versatility
synthesis
resins
Libraries
Resins
routes
Pyrrolo(2,3-d)pyrimidine

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

Solid-phase synthesis of tetrasubstituted pyrrolo[2,3-d]pyrimidines. / Lee, Ji Hoon; Lim, Hyun-Suk.

In: Organic and Biomolecular Chemistry, Vol. 10, No. 21, 07.06.2012, p. 4229-4235.

Research output: Contribution to journalArticle

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