Solitary solid renal mass: Can we predict malignancy?

Philippe Violette, Samuel Abourbih, Konrad M. Szymanski, Simon Tanguay, Armen Aprikian, Keith Matthews, Fadi Brimo, Wassim Kassouf

Research output: Contribution to journalArticle

26 Scopus citations


OBJECTIVE • To determine the clinical predictors of benign disease in patients with solitary solid renal masses. PATIENTS AND METHODS • Pathology reports of patients who underwent radical or partial nephrectomy at two hospitals from 1998 to 2008 were reviewed. • Only patients with solitary solid unilateral renal masses were included. • Predictors of malignancy risk were assessed with univariate and multivariate logistic regression analysis. RESULTS • A total of 592 patients with a mean ( SD ) age of 60 (13) years were included, 38% of whom were women. Radical and partial nephrectomy was performed in 66% and 34% of patients, respectively. • Renal masses were equally distributed on the right and left sides (49% vs 51%, P = 0.84). Masses were more commonly located in the upper and lower poles than in the mid pole (40.8% vs 38.7% vs 20.5%, respectively). • The mean tumour size was larger in patients who underwent radical compared with partial nephrectomy (6.8 cm vs 2.9 cm, P < 0.001). The rate of benign disease in our overall population was 9.5%. • On univariate and multivariate analysis, only a renal mass size < 2 cm and female gender were predictive of benign disease. On further analysis the magnitude of this effect was found to be additive. CONCLUSIONS • Renal masses < 2 cm and female gender were associated with a higher probability of benign disease. • Patient age and tumour location were not predictive of benign disease.

Original languageEnglish (US)
Pages (from-to)E548-E552
JournalBJU International
Issue number11 B
StatePublished - Dec 1 2012
Externally publishedYes


  • Benign
  • Kidney cancer
  • Malignancy
  • Renal mass

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Solitary solid renal mass: Can we predict malignancy?'. Together they form a unique fingerprint.

  • Cite this

    Violette, P., Abourbih, S., Szymanski, K. M., Tanguay, S., Aprikian, A., Matthews, K., Brimo, F., & Kassouf, W. (2012). Solitary solid renal mass: Can we predict malignancy? BJU International, 110(11 B), E548-E552.