Solitary solid renal mass: Can we predict malignancy?

Philippe Violette, Samuel Abourbih, Konrad Szymanski, Simon Tanguay, Armen Aprikian, Keith Matthews, Fadi Brimo, Wassim Kassouf

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

OBJECTIVE • To determine the clinical predictors of benign disease in patients with solitary solid renal masses. PATIENTS AND METHODS • Pathology reports of patients who underwent radical or partial nephrectomy at two hospitals from 1998 to 2008 were reviewed. • Only patients with solitary solid unilateral renal masses were included. • Predictors of malignancy risk were assessed with univariate and multivariate logistic regression analysis. RESULTS • A total of 592 patients with a mean ( SD ) age of 60 (13) years were included, 38% of whom were women. Radical and partial nephrectomy was performed in 66% and 34% of patients, respectively. • Renal masses were equally distributed on the right and left sides (49% vs 51%, P = 0.84). Masses were more commonly located in the upper and lower poles than in the mid pole (40.8% vs 38.7% vs 20.5%, respectively). • The mean tumour size was larger in patients who underwent radical compared with partial nephrectomy (6.8 cm vs 2.9 cm, P < 0.001). The rate of benign disease in our overall population was 9.5%. • On univariate and multivariate analysis, only a renal mass size < 2 cm and female gender were predictive of benign disease. On further analysis the magnitude of this effect was found to be additive. CONCLUSIONS • Renal masses < 2 cm and female gender were associated with a higher probability of benign disease. • Patient age and tumour location were not predictive of benign disease.

Original languageEnglish (US)
JournalBJU International
Volume110
Issue number11 B
DOIs
StatePublished - Dec 2012
Externally publishedYes

Fingerprint

Kidney
Nephrectomy
Neoplasms
Multivariate Analysis
Logistic Models
Regression Analysis
Pathology
Population

Keywords

  • Benign
  • Kidney cancer
  • Malignancy
  • Renal mass

ASJC Scopus subject areas

  • Urology

Cite this

Violette, P., Abourbih, S., Szymanski, K., Tanguay, S., Aprikian, A., Matthews, K., ... Kassouf, W. (2012). Solitary solid renal mass: Can we predict malignancy? BJU International, 110(11 B). https://doi.org/10.1111/j.1464-410X.2012.11245.x

Solitary solid renal mass : Can we predict malignancy? / Violette, Philippe; Abourbih, Samuel; Szymanski, Konrad; Tanguay, Simon; Aprikian, Armen; Matthews, Keith; Brimo, Fadi; Kassouf, Wassim.

In: BJU International, Vol. 110, No. 11 B, 12.2012.

Research output: Contribution to journalArticle

Violette, P, Abourbih, S, Szymanski, K, Tanguay, S, Aprikian, A, Matthews, K, Brimo, F & Kassouf, W 2012, 'Solitary solid renal mass: Can we predict malignancy?', BJU International, vol. 110, no. 11 B. https://doi.org/10.1111/j.1464-410X.2012.11245.x
Violette P, Abourbih S, Szymanski K, Tanguay S, Aprikian A, Matthews K et al. Solitary solid renal mass: Can we predict malignancy? BJU International. 2012 Dec;110(11 B). https://doi.org/10.1111/j.1464-410X.2012.11245.x
Violette, Philippe ; Abourbih, Samuel ; Szymanski, Konrad ; Tanguay, Simon ; Aprikian, Armen ; Matthews, Keith ; Brimo, Fadi ; Kassouf, Wassim. / Solitary solid renal mass : Can we predict malignancy?. In: BJU International. 2012 ; Vol. 110, No. 11 B.
@article{ac5f9d97ae5c42f58f1ff2707c4276cc,
title = "Solitary solid renal mass: Can we predict malignancy?",
abstract = "OBJECTIVE • To determine the clinical predictors of benign disease in patients with solitary solid renal masses. PATIENTS AND METHODS • Pathology reports of patients who underwent radical or partial nephrectomy at two hospitals from 1998 to 2008 were reviewed. • Only patients with solitary solid unilateral renal masses were included. • Predictors of malignancy risk were assessed with univariate and multivariate logistic regression analysis. RESULTS • A total of 592 patients with a mean ( SD ) age of 60 (13) years were included, 38{\%} of whom were women. Radical and partial nephrectomy was performed in 66{\%} and 34{\%} of patients, respectively. • Renal masses were equally distributed on the right and left sides (49{\%} vs 51{\%}, P = 0.84). Masses were more commonly located in the upper and lower poles than in the mid pole (40.8{\%} vs 38.7{\%} vs 20.5{\%}, respectively). • The mean tumour size was larger in patients who underwent radical compared with partial nephrectomy (6.8 cm vs 2.9 cm, P < 0.001). The rate of benign disease in our overall population was 9.5{\%}. • On univariate and multivariate analysis, only a renal mass size < 2 cm and female gender were predictive of benign disease. On further analysis the magnitude of this effect was found to be additive. CONCLUSIONS • Renal masses < 2 cm and female gender were associated with a higher probability of benign disease. • Patient age and tumour location were not predictive of benign disease.",
keywords = "Benign, Kidney cancer, Malignancy, Renal mass",
author = "Philippe Violette and Samuel Abourbih and Konrad Szymanski and Simon Tanguay and Armen Aprikian and Keith Matthews and Fadi Brimo and Wassim Kassouf",
year = "2012",
month = "12",
doi = "10.1111/j.1464-410X.2012.11245.x",
language = "English (US)",
volume = "110",
journal = "BJU International",
issn = "1464-4096",
publisher = "Wiley-Blackwell",
number = "11 B",

}

TY - JOUR

T1 - Solitary solid renal mass

T2 - Can we predict malignancy?

AU - Violette, Philippe

AU - Abourbih, Samuel

AU - Szymanski, Konrad

AU - Tanguay, Simon

AU - Aprikian, Armen

AU - Matthews, Keith

AU - Brimo, Fadi

AU - Kassouf, Wassim

PY - 2012/12

Y1 - 2012/12

N2 - OBJECTIVE • To determine the clinical predictors of benign disease in patients with solitary solid renal masses. PATIENTS AND METHODS • Pathology reports of patients who underwent radical or partial nephrectomy at two hospitals from 1998 to 2008 were reviewed. • Only patients with solitary solid unilateral renal masses were included. • Predictors of malignancy risk were assessed with univariate and multivariate logistic regression analysis. RESULTS • A total of 592 patients with a mean ( SD ) age of 60 (13) years were included, 38% of whom were women. Radical and partial nephrectomy was performed in 66% and 34% of patients, respectively. • Renal masses were equally distributed on the right and left sides (49% vs 51%, P = 0.84). Masses were more commonly located in the upper and lower poles than in the mid pole (40.8% vs 38.7% vs 20.5%, respectively). • The mean tumour size was larger in patients who underwent radical compared with partial nephrectomy (6.8 cm vs 2.9 cm, P < 0.001). The rate of benign disease in our overall population was 9.5%. • On univariate and multivariate analysis, only a renal mass size < 2 cm and female gender were predictive of benign disease. On further analysis the magnitude of this effect was found to be additive. CONCLUSIONS • Renal masses < 2 cm and female gender were associated with a higher probability of benign disease. • Patient age and tumour location were not predictive of benign disease.

AB - OBJECTIVE • To determine the clinical predictors of benign disease in patients with solitary solid renal masses. PATIENTS AND METHODS • Pathology reports of patients who underwent radical or partial nephrectomy at two hospitals from 1998 to 2008 were reviewed. • Only patients with solitary solid unilateral renal masses were included. • Predictors of malignancy risk were assessed with univariate and multivariate logistic regression analysis. RESULTS • A total of 592 patients with a mean ( SD ) age of 60 (13) years were included, 38% of whom were women. Radical and partial nephrectomy was performed in 66% and 34% of patients, respectively. • Renal masses were equally distributed on the right and left sides (49% vs 51%, P = 0.84). Masses were more commonly located in the upper and lower poles than in the mid pole (40.8% vs 38.7% vs 20.5%, respectively). • The mean tumour size was larger in patients who underwent radical compared with partial nephrectomy (6.8 cm vs 2.9 cm, P < 0.001). The rate of benign disease in our overall population was 9.5%. • On univariate and multivariate analysis, only a renal mass size < 2 cm and female gender were predictive of benign disease. On further analysis the magnitude of this effect was found to be additive. CONCLUSIONS • Renal masses < 2 cm and female gender were associated with a higher probability of benign disease. • Patient age and tumour location were not predictive of benign disease.

KW - Benign

KW - Kidney cancer

KW - Malignancy

KW - Renal mass

UR - http://www.scopus.com/inward/record.url?scp=84876442989&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876442989&partnerID=8YFLogxK

U2 - 10.1111/j.1464-410X.2012.11245.x

DO - 10.1111/j.1464-410X.2012.11245.x

M3 - Article

C2 - 22612453

AN - SCOPUS:84876442989

VL - 110

JO - BJU International

JF - BJU International

SN - 1464-4096

IS - 11 B

ER -