Sources of rats free of latent Pneumocystis carinii

M. S. Bartlett, M. M. Durkin, M. A. Jay, S. F. Queener, J. W. Smith

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Two sources of rats free of latent Pneumocystis carinii are described. First, rats from a virus-free colony failed to develop infection after 8 weeks of immune suppression unless they were housed with previously infected rats. Second, pregnant rats (non-virus free) received trimethoprim-sulfamethoxazole from day 10 of gestation until the pups were weaned. Pups raised in filter-topped cages and immunosuppressed for 8 weeks were free of P. carinii infection.

Original languageEnglish (US)
Pages (from-to)1794-1795
Number of pages2
JournalJournal of clinical microbiology
Volume25
Issue number9
StatePublished - Nov 6 1987
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)

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    Bartlett, M. S., Durkin, M. M., Jay, M. A., Queener, S. F., & Smith, J. W. (1987). Sources of rats free of latent Pneumocystis carinii. Journal of clinical microbiology, 25(9), 1794-1795.