Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

Amer M. Zeidan, Prajwal C. Boddu, Mrinal M. Patnaik, Jan Philipp Bewersdorf, Maximilian Stahl, Raajit K. Rampal, Rory Shallis, David P. Steensma, Michael R. Savona, Mikkael A. Sekeres, Gail J. Roboz, Daniel J. DeAngelo, Andre C. Schuh, Eric Padron, Joshua F. Zeidner, Roland B. Walter, Francesco Onida, Amir Fathi, Amy DeZern, Gabriela HobbsEytan M. Stein, Paresh Vyas, Andrew H. Wei, David T. Bowen, Pau Montesinos, Elizabeth A. Griffiths, Amit K. Verma, Alla Keyzner, Michal Bar-Natan, Shyamala C. Navada, Marina Kremyanskaya, Aaron D. Goldberg, Aref Al-Kali, Mark L. Heaney, Aziz Nazha, Huda Salman, Selina Luger, Keith W. Pratz, Heiko Konig, Rami Komrokji, Michael Deininger, Blanca Xicoy Cirici, Vijaya Raj Bhatt, Lewis R. Silverman, Harry P. Erba, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Eunice S. Wang, Martin S. Tallman, Richard M. Stone, John Mascarenhas

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 is a global public health crisis. Multiple observations indicate poorer post-infection outcomes for patients with cancer than for the general population. Herein, we highlight the challenges in caring for patients with acute leukaemias and myeloid neoplasms amid the COVID-19 pandemic. We summarise key changes related to service allocation, clinical and supportive care, clinical trial participation, and ethical considerations regarding the use of lifesaving measures for these patients. We recognise that these recommendations might be more applicable to high-income countries and might not be generalisable because of regional differences in health-care infrastructure, individual circumstances, and a complex and highly fluid health-care environment. Despite these limitations, we aim to provide a general framework for the care of patients with acute leukaemias and myeloid neoplasms during the COVID-19 pandemic on the basis of recommendations from international experts.

Original languageEnglish (US)
Pages (from-to)e601-e612
JournalThe Lancet Haematology
Volume7
Issue number8
DOIs
StatePublished - Aug 2020

ASJC Scopus subject areas

  • Hematology

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