Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars

Byron Batteiger, Pei Mao Lin, Robert B. Jones, Barbara J. Van Der Pol

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13 Citations (Scopus)

Abstract

Synthetic peptides and murine monoclonal antibodies were used to map cross-reactive chlamydial epitopes. A species-specific epitope in the central region of variable sequence region 4 abuts the amino-terminal end of a B- serogroup-specific or F/G-serogroup-specific epitope, which in turn abuts known serovar-specific epitopes. The carboxyl-terminal portion of variable sequence region 4 (residues 297 to 314) comprises a region of end-to-end B- cell epitopes in some serovars of the B and F/G serogroups.

Original languageEnglish
Pages (from-to)2839-2841
Number of pages3
JournalInfection and Immunity
Volume64
Issue number7
StatePublished - 1996

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Epitopes
B-Lymphocyte Epitopes
Monoclonal Antibodies
Chlamydia trachomatis omp1 protein
Serogroup
Peptides

ASJC Scopus subject areas

  • Immunology

Cite this

Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars. / Batteiger, Byron; Lin, Pei Mao; Jones, Robert B.; Van Der Pol, Barbara J.

In: Infection and Immunity, Vol. 64, No. 7, 1996, p. 2839-2841.

Research output: Contribution to journalArticle

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