Specificity of lactoferrin as an inhibitor of granulocyte-macrophage colony-stimulating activity production from fetal mouse liver cells

J. R. Zucali, Hal Broxmeyer, J. A. Ulatowski

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Fetal mouse liver cultures capable of producing both erythropoietin (Ep) and granulocyte-macrophage colony stimulating activity (GM-CSA) were used to study the specificity of lactoferrin as an inhibitor of the production of GM-CSA. Both a granulocyte-derived colony-inhibiting activity (CIA) and lactoferrin inhibited GM-CSA production while having no effect on Ep production. These results demonstrate the specificity of lactoferrin for GM-CSA production.

Original languageEnglish (US)
Pages (from-to)951-954
Number of pages4
JournalBlood
Volume54
Issue number4
StatePublished - 1979
Externally publishedYes

Fingerprint

Fetal Movement
Lactoferrin
Macrophages
Granulocytes
Liver
Erythropoietin

ASJC Scopus subject areas

  • Hematology

Cite this

Specificity of lactoferrin as an inhibitor of granulocyte-macrophage colony-stimulating activity production from fetal mouse liver cells. / Zucali, J. R.; Broxmeyer, Hal; Ulatowski, J. A.

In: Blood, Vol. 54, No. 4, 1979, p. 951-954.

Research output: Contribution to journalArticle

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