Speculations on the Role of Transmissible Agents in the Pathogenesis of Alzheimer's Disease

Ashley T. Haase, Elizabeth Lewis, Stephen Wietgrefe, Mary Zupancic, Diedrich Jane, Hal Minnigan, Melvyn J. Ball

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Unconventional agents and conventional viruses provide model systems to investigate the pathogenesis of Alzheimer's disease (AD). The essay which follows examines the hypothetical role of herpes simplex in AD and presents some generally applicable experimental approaches to detecting genes in brain tissues. The concluding section, on parallels between AD and diseases of the brain caused by unconventional viruses, defines strategies for isolating genes related to pathology.

Original languageEnglish (US)
Pages (from-to)449-451
Number of pages3
JournalCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Volume13
Issue numberS4
DOIs
StatePublished - Nov 1986
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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