Sphincter of Oddi Dysfunction

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Sphincter of Oddi dysfunction (SOD) refers to a motor abnormality of the sphincter of Oddi, typically resulting in a hypertonic sphincter, and may be manifested clinically by chronic abdominal pain, pancreatitis, or abnormal liver function tests. In this chapter, we discuss the classification systems typically used in SOD, as well as the epidemiology of this controversial disease. The diagnostic criteria for SOD and appropriate evaluation of patients are reviewed. Both non-invasive and invasive diagnostic methods are discussed. Sphincter of Oddi manometry (SOM) is the only available method to measure motor activity directly, and is considered currently to be the diagnostic gold standard. Indications, performance, and complications of this technique are reviewed. Therapy for SOD is discussed, using an evidence-based approach.

Original languageEnglish (US)
Title of host publicationAdvanced Digestive Endoscopy
Subtitle of host publicationERCP
PublisherBlackwell Publishing Ltd
Number of pages34
ISBN (Print)9781405120791
StatePublished - Oct 25 2007


  • Endoscopic ultrasound monitoring
  • Morphine-prostigmin provocative test (nardi test)
  • Serum chemistries
  • Sphincter of oddi dysfunction (SOD)
  • Standard imaging

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Fogel, E. L., & Sherman, S. (2007). Sphincter of Oddi Dysfunction. In Advanced Digestive Endoscopy: ERCP (pp. 165-198). Blackwell Publishing Ltd. https://doi.org/10.1002/9780470987490.ch8