Spinal claudication in systemic amyloidosis

N. Harats, R. Worth, M. D. Benson

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


We describe a patient with hereditary amyloidosis who developed the syndrome of spinal claudication. Myelography and computerized tomography of the lumbar spine demonstrated stenosis of the spinal canal and surgical exploration confirmed dense amyloid infiltration of ligamentous structures compressing the nerve roots. Two cousins of our patient and 2 patients with immunoglobulin amyloidosis had similar clinical syndromes. Spinal stenosis can be demonstrated by myelography or by computerized tomography. Diagnosis of this syndrome is important since wide decompression may be needed to relieve symptoms. Patients who had only disc extraction did not improve after the operation; their symptoms persisted and even worsened.

Original languageEnglish (US)
Pages (from-to)1003-1006
Number of pages4
JournalJournal of Rheumatology
Issue number7
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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