Purpose of Review: The incidence of spinal epidural abscess is increasing, and the understanding of the pathophysiology is evolving. Better understanding of the pathophysiology, specifically the role of ischemia, warrants a change in therapy. Recent Findings: Paralysis in spinal epidural abscess may be the result of spinal cord compression, spinal cord arterial and/or venous ischemia and thrombophlebitis or a combination of these. Summary: Recent evidence indicates the following areas of investigation and management can improve outcome in spinal epidural abscess: minimally invasive surgery early versus medical management when there are no significant neurological deficits, neuroradiologic arterial evaluation with therapies directed at vascular ischemia and thrombosis, and aggressive rehabilitation.
- spinal cord compression
- spinal epidural abscess
- spinal infection
ASJC Scopus subject areas
- Clinical Neurology
TY - JOUR
T1 - Spinal epidural abscess and paralytic mechanisms
AU - Shah, Nirav H.
AU - Roos, Karen
PY - 2013/6
Y1 - 2013/6
N2 - Lippincott Williams & Wilkins.
AB - Lippincott Williams & Wilkins.
KW - spinal cord compression
KW - spinal epidural abscess
KW - spinal infection
UR - http://www.scopus.com/inward/record.url?scp=84877691073&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84877691073&partnerID=8YFLogxK
U2 - 10.1097/WCO.0b013e3283608430
DO - 10.1097/WCO.0b013e3283608430
M3 - Article
VL - 26
SP - 314
EP - 317
JO - Current Opinion in Neurology
JF - Current Opinion in Neurology
SN - 1350-7540
IS - 3