Spondyloarthropathies: Update on diagnosis and therapy

Mazen Elyan, Muhammad Asim Khan

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The spondyloarthropathies are strongly associated with the HLA-B27 gene. The diagnosis is based primarily on clinical findings. Ankylosing spondylitis often involves the sacroiliac joints and spine. Psoriatic arthritis occurs in up to one-third of patients with psoriasis. Reactive arthritis must be distinguished from other arthropathies. Arthritis occurs in about 30% of patients with inflammatory bowel disease. Undifferentiated spondyloarthropathy includes several related disorders. Radiographic evidence of sacroiliitis is a characteristic feature of ankylosing spondylitis. Management of spondyloarthropathies should include patient education and regular exercise. NSAIDs are the first line of treatment. The tumor necrosis factor-α inhibitors are highly effective in patients with active ankylosing spondylitis and in those with psoriatic arthritis that is unresponsive to conventional therapy.

Original languageEnglish (US)
Pages (from-to)681-691
Number of pages11
JournalConsultant
Volume48
Issue number9
StatePublished - Aug 1 2008

Fingerprint

Spondylarthropathies
Ankylosing Spondylitis
Psoriatic Arthritis
Sacroiliitis
Sacroiliac Joint
HLA-B27 Antigen
Reactive Arthritis
Joint Diseases
Non-Steroidal Anti-Inflammatory Agents
Patient Education
Inflammatory Bowel Diseases
Psoriasis
Arthritis
Spine
Therapeutics
Tumor Necrosis Factor-alpha
Exercise
Genes

Keywords

  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Reactive arthritis
  • Spondyloarthropathy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Elyan, M., & Khan, M. A. (2008). Spondyloarthropathies: Update on diagnosis and therapy. Consultant, 48(9), 681-691.

Spondyloarthropathies : Update on diagnosis and therapy. / Elyan, Mazen; Khan, Muhammad Asim.

In: Consultant, Vol. 48, No. 9, 01.08.2008, p. 681-691.

Research output: Contribution to journalArticle

Elyan, M & Khan, MA 2008, 'Spondyloarthropathies: Update on diagnosis and therapy', Consultant, vol. 48, no. 9, pp. 681-691.
Elyan M, Khan MA. Spondyloarthropathies: Update on diagnosis and therapy. Consultant. 2008 Aug 1;48(9):681-691.
Elyan, Mazen ; Khan, Muhammad Asim. / Spondyloarthropathies : Update on diagnosis and therapy. In: Consultant. 2008 ; Vol. 48, No. 9. pp. 681-691.
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