Spontaneous and induced interferon production by peripheral blood leucocytes from control population and patients with herpes genitalis

D. Iannello, M. W. Taylor, Kenneth Fife, L. Chen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The spontaneous and PHA induced levels of interferon were measured in peripheral blood leucocyte cultures of twenty-eight individuals diagnosed as positive for herpes genitalis, and in a group of control subjects. As reported by Cunningham and Merigan [1983] for herpes labialis, leucocytes from individuals with herpes genitalis produced low levels of interferon spontaneously; however, similar results were found for individuals within the control population. No statistically significant difference could be found for PHA induced interferon levels, antigen induced interferon levels, or helper/suppressor cell ratios between the herpes genitalis population and control population. Our results indicated that interferon does not play a major role in the latency or recurrence of herpes genitalis.

Original languageEnglish
Pages (from-to)25-34
Number of pages10
JournalJournal of Medical Virology
Volume22
Issue number1
StatePublished - 1987

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Herpes Genitalis
Interferons
Leukocytes
Population
Herpes Labialis
Population Control
Helper-Inducer T-Lymphocytes
Antigens
Recurrence
Control Groups

ASJC Scopus subject areas

  • Virology

Cite this

Spontaneous and induced interferon production by peripheral blood leucocytes from control population and patients with herpes genitalis. / Iannello, D.; Taylor, M. W.; Fife, Kenneth; Chen, L.

In: Journal of Medical Virology, Vol. 22, No. 1, 1987, p. 25-34.

Research output: Contribution to journalArticle

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